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APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.
Published in:
Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abc9375
By:
- Liu, Chia-Chen;
- Murray, Melissa E.;
- Li, Xia;
- Zhao, Na;
- Wang, Na;
- Heckman, Michael G.;
- Shue, Francis;
- Martens, Yuka;
- Li, Yonghe;
- Raulin, Ana-Caroline;
- Rosenberg, Cassandra L.;
- Doss, Sydney V.;
- Zhao, Jing;
- Wren, Melissa C.;
- Jia, Lin;
- Ren, Yingxue;
- Ikezu, Tadafumi C.;
- Lu, Wenyan;
- Fu, Yuan;
- Caulfield, Thomas
Publication type:
Article
Role of Wnt Co-Receptor LRP6 in Triple Negative Breast Cancer Cell Migration and Invasion.
Published in:
Journal of Cellular Biochemistry, 2017, v. 118, n. 9, p. 2968, doi. 10.1002/jcb.25956
By:
- Ma, Jinlu;
- Lu, Wenyan;
- Chen, Dongquan;
- Xu, Bo;
- Li, Yonghe
Publication type:
Article
Salinomycin Suppresses LRP6 Expression and Inhibits Both Wnt/β-catenin and mTORC1 Signaling in Breast and Prostate Cancer Cells.
Published in:
Journal of Cellular Biochemistry, 2014, v. 115, n. 10, p. 1799, doi. 10.1002/jcb.24850
By:
- Lu, Wenyan;
- Li, Yonghe
Publication type:
Article
Discovery of a novel inhibitor of kinesin-like protein KIFC1.
Published in:
Biochemical Journal, 2016, v. 473, n. 8, p. 1027, doi. 10.1042/BJ20150992
By:
- Wei Zhang;
- Ling Zhai;
- Yimin Wang;
- Boohaker, Rebecca J.;
- Wenyan Lu;
- Gupta, Vandana V.;
- Padmalayam, Indira;
- Bostwick, Robert J.;
- Lucile White, E.;
- Ross, Larry J.;
- Maddry, Joseph;
- Ananthan, Subramaniam;
- Augelli-Szafran, Corinne E.;
- Suto, Mark J.;
- Bo Xu;
- Rongbao Li;
- Yonghe Li
Publication type:
Article
LRP6 expression promotes cancer cell proliferation and tumorigenesis by alteringß-catenin subcellular distribution.
Published in:
Oncogene, 2004, v. 23, n. 56, p. 9129, doi. 10.1038/sj.onc.1208123
By:
- Yonghe Li;
- Wenyan Lu;
- Xi He;
- Schwartz, Alan L.;
- Guojun Bu
Publication type:
Article
APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19264-0
By:
- Zhao, Jing;
- Fu, Yuan;
- Yamazaki, Yu;
- Ren, Yingxue;
- Davis, Mary D.;
- Liu, Chia-Chen;
- Lu, Wenyan;
- Wang, Xue;
- Chen, Kai;
- Cherukuri, Yesesri;
- Jia, Lin;
- Martens, Yuka A.;
- Job, Lucy;
- Shue, Francis;
- Nguyen, Thanh Thanh;
- Younkin, Steven G.;
- Graff-Radford, Neill R.;
- Wszolek, Zbigniew K.;
- Brafman, David A.;
- Asmann, Yan W.
Publication type:
Article
A novel histone deacetylase inhibitor W2A-16 improves the barrier integrity in brain vascular endothelial cells.
Published in:
Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1368018
By:
- Yasuteru Inoue;
- Yingxue Ren;
- Shuwen Zhang;
- Bamkole, Michael;
- Islam, Naeyma N.;
- Selvaraj, Manikandan;
- Wenyan Lu;
- Caulfield, Thomas R.;
- Yonghe Li;
- Takahisa Kanekiyo
Publication type:
Article
Sorting nexin 17 facilitates LRP recycling in the early endosome.
Published in:
EMBO Journal, 2005, v. 24, n. 16, p. 2851, doi. 10.1038/sj.emboj.7600756
By:
- van Kerkhof, Peter;
- Jiyeon Lee;
- McCormick, Lynn;
- Tetrault, Elena;
- Wenyan Lu;
- Schoenfish, Marissa;
- Oorschot, Viola;
- Strous, Ger J.;
- Klumperman, Judith;
- Bu, Guojun
Publication type:
Article
Pharmacological inhibition of sFRP1 stimulates the non‐amyloidogenic pathway of amyloid precursor protein proteolytic processing.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.076527
By:
- Lu, Wenyan;
- Macyczko, Jesse R;
- Martens, Yuka A;
- Bu, Guojun;
- Kanekiyo, Takahisa;
- Li, Yonghe
Publication type:
Article
Effect of Impounding on Bedrock Temperature of High Arch Dam Site: A Case Study of the Xiluodu Project, China.
Published in:
Water (20734441), 2023, v. 15, n. 2, p. 340, doi. 10.3390/w15020340
By:
- Zhang, Linfei;
- Ren, Qingwen;
- Shen, Lei;
- Lu, Wenyan;
- Tao, Mei;
- Gu, Jiafeng
Publication type:
Article
Size, number and phospholipid composition of milk fat globules are affected by dietary conjugated linoleic acid.
Published in:
Journal of Animal Physiology & Animal Nutrition, 2023, v. 107, n. 4, p. 995, doi. 10.1111/jpn.13788
By:
- Zhang, Menglu;
- Fu, Tong;
- Huang, Qixue;
- Xing, Zhiyang;
- Yang, Jingna;
- Lu, Wenyan;
- Hu, Mingyue;
- Han, Li Qiang;
- Loor, Juan J.;
- Gao, Teng Yun
Publication type:
Article
Comparisons of constitutive resistances to soybean cyst nematode between PI 88788- and Peking-type sources of resistance in soybean by transcriptomic and metabolomic profilings.
Published in:
Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.1055867
By:
- Shanshan Chu;
- Hui Ma;
- Ke Li;
- Junfeng Li;
- Hongli Liu;
- Leipo Quan;
- Xuling Zhu;
- Meiling Chen;
- Wenyan Lu;
- Xiaoming Chen;
- Xuelian Qu;
- Jiaqi Xu;
- Yun Lian;
- Weiguo Lu;
- Erhui Xiong;
- Yongqing Jiao
Publication type:
Article
Correction to: Apolipoprotein E regulates lipid metabolism and α‑synuclein pathology in human iPSC‑derived cerebral organoids.
Published in:
2022
By:
- Zhao, Jing;
- Lu, Wenyan;
- Ren, Yingxue;
- Fu, Yuan;
- Martens, Yuka A.;
- Shue, Francis;
- Davis, Mary D.;
- Wang, Xue;
- Chen, Kai;
- Li, Fuyao;
- Liu, Chia-Chen;
- Graff-Radford, Neill R.;
- Wszolek, Zbigniew K.;
- Younkin, Steven G.;
- Brafman, David A.;
- Ertekin-Taner, Nilüfer;
- Asmann, Yan W.;
- Dickson, Dennis W.;
- Xu, Ziying;
- Pan, Meixia
Publication type:
Correction Notice
Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.
Published in:
Acta Neuropathologica, 2021, v. 142, n. 5, p. 807, doi. 10.1007/s00401-021-02361-9
By:
- Zhao, Jing;
- Lu, Wenyan;
- Ren, Yingxue;
- Fu, Yuan;
- Martens, Yuka A.;
- Shue, Francis;
- Davis, Mary D.;
- Wang, Xue;
- Chen, Kai;
- Li, Fuyao;
- Liu, Chia-Chen;
- Graff-Radford, Neill R.;
- Wszolek, Zbigniew K.;
- Younkin, Steven G.;
- Brafman, David A.;
- Ertekin-Taner, Nilüfer;
- Asmann, Yan W.;
- Dickson, Dennis W.;
- Xu, Ziying;
- Pan, Meixia
Publication type:
Article
Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.
Published in:
2021
By:
- Zhao, Jing;
- Fu, Yuan;
- Yamazaki, Yu;
- Ren, Yingxue;
- Davis, Mary D.;
- Liu, Chia-Chen;
- Lu, Wenyan;
- Wang, Xue;
- Chen, Kai;
- Cherukuri, Yesesri;
- Jia, Lin;
- Martens, Yuka A.;
- Job, Lucy;
- Shue, Francis;
- Nguyen, Thanh Thanh;
- Younkin, Steven G.;
- Graff-Radford, Neill R.;
- Wszolek, Zbigniew K.;
- Brafman, David A.;
- Asmann, Yan W.
Publication type:
Correction Notice
Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo
Published in:
FEBS Letters, 2011, v. 585, n. 19, p. 3120, doi. 10.1016/j.febslet.2011.08.046
By:
- Lin, Cuihong;
- Lu, Wenyan;
- Zhai, Ling;
- Bethea, Traci;
- Berry, Kristy;
- Qu, Zhican;
- Waud, William R.;
- Li, Yonghe
Publication type:
Article
The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/β-Catenin Signaling in Cancer Cells.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0058102
By:
- Lin, Cuihong;
- Lu, Wenyan;
- Zhang, Wei;
- Londoño-Joshi, Angelina I.;
- Buchsbaum, Donald J.;
- Bu, Guojun;
- Li, Yonghe
Publication type:
Article
Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway.
Published in:
PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029290
By:
- Wenyan Lu;
- Cuihong Lin;
- Roberts, Michael J.;
- Waud, William R.;
- Piazza, Gary A.;
- Yonghe Li
Publication type:
Article
Dkk1 Stabilizes Wnt Co-Receptor LRP6: Implication for Wnt Ligand-Induced LRP6 Down-Regulation.
Published in:
PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0011014
By:
- Yonghe Li;
- Wenyan Lu;
- King, Taj D.;
- Chia-Chen Liu;
- Bijur, Gautam N.;
- Guojun Bu
Publication type:
Article
Discovery of Novel Allosteric Eg5 Inhibitors Through Structure-Based Virtual Screening.
Published in:
Chemical Biology & Drug Design, 2016, v. 88, n. 2, p. 178, doi. 10.1111/cbdd.12744
By:
- Zhang, Wei;
- Zhai, Ling;
- Lu, Wenyan;
- Boohaker, Rebecca J.;
- Padmalayam, Indira;
- Li, Yonghe
Publication type:
Article
Novel Wnt modulators for the treatment of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.063223
By:
- Li, Yonghe;
- Caulfield, Thomas R.;
- Macyczko, Jesse R;
- Wang, Na;
- Jia, Lin;
- Shue, Francis;
- Lu, Wenyan;
- Zhao, Jing;
- Martens, Yuka A;
- Liu, Chia‐Chen;
- Bu, Guojun
Publication type:
Article
APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids.
Published in:
Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03444-y
By:
- Zhao, Jing;
- Ikezu, Tadafumi C.;
- Lu, Wenyan;
- Macyczko, Jesse R.;
- Li, Yonghe;
- Lewis-Tuffin, Laura J.;
- Martens, Yuka A.;
- Ren, Yingxue;
- Zhu, Yiyang;
- Asmann, Yan W.;
- Ertekin-Taner, Nilüfer;
- Kanekiyo, Takahisa;
- Bu, Guojun
Publication type:
Article
LRP1 is a neuronal receptor for α-synuclein uptake and spread.
Published in:
Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00560-w
By:
- Chen, Kai;
- Martens, Yuka A.;
- Meneses, Axel;
- Ryu, Daniel H.;
- Lu, Wenyan;
- Raulin, Ana Caroline;
- Li, Fuyao;
- Zhao, Jing;
- Chen, Yixing;
- Jin, Yunjung;
- Linares, Cynthia;
- Goodwin, Marshall;
- Li, Yonghe;
- Liu, Chia-Chen;
- Kanekiyo, Takahisa;
- Holtzman, David M.;
- Golde, Todd E.;
- Bu, Guojun;
- Zhao, Na
Publication type:
Article
Deformation Analysis of Large Diameter Monopiles of Offshore Wind Turbines under Scour.
Published in:
Applied Sciences (2076-3417), 2020, v. 10, n. 21, p. 7579, doi. 10.3390/app10217579
By:
- Wang, Zhaoyao;
- Hu, Ruigeng;
- Leng, Hao;
- Liu, Hongjun;
- Bai, Yifan;
- Lu, Wenyan
Publication type:
Article
A Fast Frequency Domain Method for Steady-State Solution of Forced Vibration of System with Complex Damping.
Published in:
Applied Sciences (2076-3417), 2020, v. 10, n. 10, p. 3442, doi. 10.3390/app10103442
By:
- Qi, Wenrui;
- Pan, Danguang;
- Gao, Yongtao;
- Lu, Wenyan;
- Huang, Ying
Publication type:
Article
WGCNA and transcriptome profiling reveal hub genes for key development stage seed size/oil content between wild and cultivated soybean.
Published in:
BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09617-6
By:
- Yao, Yanjie;
- Xiong, Erhui;
- Qu, Xuelian;
- Li, Junfeng;
- Liu, Hongli;
- Quan, Leipo;
- Lu, Wenyan;
- Zhu, Xuling;
- Chen, Meiling;
- Li, Ke;
- Chen, Xiaoming;
- Lian, Yun;
- Lu, Weiguo;
- Zhang, Dan;
- Zhou, Xinan;
- Chu, Shanshan;
- Jiao, Yongqing
Publication type:
Article
Unsupervised Domain Adaptation Damage Identification Approach of High Arch Dams after Earthquakes.
Published in:
Structural Control & Health Monitoring, 2023, p. 1, doi. 10.1155/2023/6349167
By:
- Xiangyu, Cao;
- Liang, Chen;
- Jianyun, Chen;
- Jing, Li;
- Wenyan, Lu;
- Haixiang, Liu;
- Liu, Pengfei;
- Minyong, Ke;
- Yunqing, Tang
Publication type:
Article
Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases.
Published in:
International Journal of Cancer, 2008, v. 123, n. 5, p. 1034, doi. 10.1002/ijc.23625
By:
- Bu, Guojun;
- Lu, Wenyan;
- Liu, Chia-Chen;
- Selander, Katri;
- Yoneda, Toshiyuki;
- Hall, Christopher;
- Keller, Evan T.;
- Li, Yonghe
Publication type:
Article
R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression
Published in:
FEBS Letters, 2008, v. 582, n. 5, p. 643, doi. 10.1016/j.febslet.2008.01.035
By:
- Lu, Wenyan;
- Kim, Kyung-Ah;
- Liu, Jianzhong;
- Abo, Arie;
- Feng, Xu;
- Cao, Xu;
- Li, Yonghe
Publication type:
Article
Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd
Published in:
FEBS Letters, 2006, v. 580, n. 22, p. 5423, doi. 10.1016/j.febslet.2006.09.011
By:
- Li, Yonghe;
- Lu, Wenyan;
- He, Xi;
- Bu, Guojun
Publication type:
Article
Essential role of the low density lipoprotein receptor-related protein in vascular smooth muscle cell migration
Published in:
FEBS Letters, 2003, v. 555, n. 2, p. 346, doi. 10.1016/S0014-5793(03)01272-9
By:
- Li, Yonghe;
- Lu, Wenyan;
- Bu, Guojun
Publication type:
Article
Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer's Disease.
Published in:
Molecular Neurobiology, 2023, v. 60, n. 1, p. 26, doi. 10.1007/s12035-022-03065-1
By:
- Macyczko, Jesse R.;
- Wang, Na;
- Zhao, Jing;
- Ren, Yingxue;
- Lu, Wenyan;
- Ikezu, Tadafumi C.;
- Zhao, Na;
- Liu, Chia-Chen;
- Bu, Guojun;
- Li, Yonghe
Publication type:
Article
On the use of mathematically-derived traits in QTL mapping.
Published in:
Molecular Breeding, 2012, v. 29, n. 3, p. 661, doi. 10.1007/s11032-011-9580-z
By:
- Wang, Yu;
- Li, Huihui;
- Zhang, Luyan;
- Lü, Wenyan;
- Wang, Jiankang
Publication type:
Article

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