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- Title
Decrease Recurrence Rate of Condylomata Acuminata by Photodynamic Therapy Combined with CO<sub>2</sub> Laser in Mainland China: A Meta-Analysis.
- Authors
Zhu, Xiaoling; Chen, Hongxiao; Cai, Longfeng; Yu, Zhiming; Cai, Limin
- Abstract
Background: Condylomata acuminata (CA) are caused by human papillomavirus. Most conventional therapies for CA have high recurrence rate. Objectives: To compare the recurrence rate of 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) combined with CO2 laser and CO2 laser alone for CA treatment in mainland China. Methods: In this meta-analysis, 2,048 cases of CA from 22 articles were divided into two groups. The treatment group was treated by using ALA-PDT combined with CO2 laser, and CO2 laser alone was applied in the control group. The recurrence rate of the two groups was calculated and compared. Results: The recurrence rate was 42.67% (451/1,057) in the control group and 10.29% (102/991) in the treatment group, with a significant statistical difference between the two groups (χ2 = 271.98, p < 0.0001). Conclusion: ALA-PDT combined with CO2 laser was more effective in decreasing the recurrence rate of CA compared with CO2 laser alone. It might offer a wide clinical application for CA treatment. Copyright © 2013 S. Karger AG, Basel
- Publication
Dermatology (10188665), 2013, Vol 225, Issue 4, p364
- ISSN
1018-8665
- Publication type
Article
- DOI
10.1159/000346330