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- Title
Kaposi's sarcoma after liver transplantation.
- Authors
Besnard, V.; Euvrard, S.; Kanitakis, J.; Mion, F.; Boillot, O.; Françès, C.; Faure, M.; Claudy, A.; Françès, C
- Abstract
<bold>Background: </bold>Kaposi's sarcoma (KS), is a known complication following kidney transplantation. It has been reported more rarely following liver transplantation.<bold>Objective: </bold>To assess the clinico-epidemiologic data of KS after liver transplantation.<bold>Methods: </bold>150 liver graft recipients were examined; those presenting with KS were studied clinically, histologically and virologically.<bold>Results: </bold>Three cases of KS were observed. The three patients had been treated with OKT3 antiserum in addition to the standard regimen. The delay of appearance varied from 5 to 36 months. Two patients had a few cutaneous lesions and 1 had more extensive involvement; none of them had visceral localizations. In 2 cases, herpesvirus-like DNA sequences were detected within the lesions. Therapy consisted in decreasing the immunosuppressive treatment, in association with alpha-interferon or vindesine in 2 cases, respectively. All patients were alive after a follow-up of 19-45 months.<bold>Conclusion: </bold>KS seems relatively frequent (2%) and appears within a short delay after liver transplantation; the prognosis may be more favourable than previously reported.
- Publication
Dermatology (10188665), 1996, Vol 193, Issue 2, p100
- ISSN
1018-8665
- Publication type
journal article
- DOI
10.1159/000246221