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- Title
TUBERCULOSE LATENTE EM PACIENTES PSORIÁSICOS TRATADOS COM IMUNOBIOLÓGICOS DO ESTADO DA PARAÍBA.
- Authors
Fernandes Paiva, Melina Pereira; Casado Liberal, Juan Demetrios; Palitot de Brito, Raphael Bastos; Miranda Regis, Carlos Danilo; Arruda Leite, Danilo Rangel; Ferraz da Costa, Joanne Elizabeth; Simplício de Sousa, Gerlania; Nascimento Nunes, Emanuel; Lawall Domingos, Emmanuel; Bastos Palitot, Esther
- Abstract
Objective: To investigate the prevalence and risks of tuberculosis (TB) in patients with psoriasis using immunobiologics treated at a referral center in Paraíba. Methods: This is a cross-sectional study with psoriatic individuals registered at the Psoriasis Reference Center at the University Hospita in partnership with the Specialized Center for the Dispensation of Exceptional Medicines, aged ≥ 18 years, treated with immunobiologics from September/2021 to August/2022. Results: The sample of 185 patients who met the criteria were 94 (50.8%) women, with a mean age of 51.8 ± 16.0 years,147 (79.4%) were from the capital of Paraíba. The most prevalent form of psoriasis was the vulgar plaque type, with 181 (45.9%) patients. All patients were using immunobiologicals, and the tumor necrosis factor inhibitor was the most widely used. Reactive Mantoux test was observed in 12 (6.5%) patients and strongly reactive in 5 (2.7%), and chest X-ray changes were observed in 6 patients. The 17 patients with latent TB were treated with isoniazid for 9 months, and none developed TB-disease. Conclusion: This study was imperative to know the epidemiological profile of patients with psoriasis using immunobiologics and who are exposed to a higher risk of developing TB-disease
- Publication
Arquivos de Ciências da Saúde da UNIPAR, 2023, Vol 27, Issue 10, p5948
- ISSN
1415-076X
- Publication type
Article
- DOI
10.25110/arqsaude.v27i10.2023-031