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- Title
Bone Ingrowth to Ti Fibre Knit Block with High Deformability.
- Authors
Yoko Henmi; Yoshihito Naito; Jimbo, Ryo; Yohei Jinno; Kazumitsu Sekine; Kenichi Hamada
- Abstract
Objectives: The objective of this study is to develop a Ti fibre knit block without sintering, and to evaluate its deformability and new bone formation in vivo. Material and Methods: A Ti fibre with a diameter of 150 µm was knitted to fabricate a Ti mesh tube. The mesh tube was compressed in a metal mould to fabricate porous Ti fibre knit blocks with three different porosities of 88%, 69%, and 50%. The elastic modulus and deformability were evaluated using a compression test. The knit block was implanted into bone defects of a rabbit's hind limb, and new bone formation was evaluated using micro computed tomography (micro-CT) analysis and histological analysis. Results: The knit blocks with 88% porosity showed excellent deformability, indicating potential appropriateness for bone defect filling. Although the porosities of the knit block were different, they indicated similar elastic modulus smaller than 1 GPa. The elastic modulus after deformation increased linearly as the applied compression stress increased. The micro-CT analysis indicated that in the block with 50% porosity new bone filled nearly all of the pore volume four weeks after implantation. In contrast, in the block with 88% porosity, new bone filled less than half of the pore volume even 12 weeks after implantation. The histological analysis also indicated new bone formation in the block. Conclusions: The titanium fibre knit block with high porosity is potentially appropriate for bone defect filling, indicating good bone ingrowth after porosity reduction with applied compression.
- Subjects
BONE growth; TRAUMATIC bone defects
- Publication
Journal of Oral & Maxillofacial Research, 2016, Vol 7, Issue 4, p1
- ISSN
2029-283X
- Publication type
Article
- DOI
10.5037/jomr.2016.7402