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- Title
A case report of Hailey-Hailey disease treated with fractional carbon dioxide laser.
- Authors
Gabdrafike, Zivile; Blazeviciute, Monika; Janonyte, Ugne; Makstiene, Jurgita; Valiukeviciene, Skaidra
- Abstract
Hailey-Hailey disease (HHD), or familial benign pemphigus, is a rare genetic condition characterized by recurrent blisters and erosions with a predilection for intertriginous areas. There is no specific treatment for HHD. Topical and systemic treatments tend to provide temporary remission. Alternative treatment (surgical interventions such as dermabrasion, excision, and laser) has been shown to prolong remission. Considering the risk of complications associated with surgical modalities, laser is often preferred as an alternative for patients failing to respond to first-line therapies. We report a case of recalcitrant HHD successfully treated with a fractional ablative CO2 laser procedure (wavelength of 10600 nm, power of 7-10 W, 2-3 passes) on a 35-year-old female. The patient has a 7-year history of therapy-resistant HHD. A 2-month followup showed substantially resolved lesions, with mild erythema and post-inflammatory hyperpigmentation in treated areas.
- Subjects
CARBON dioxide lasers; REPORTING of diseases; PREOPERATIVE risk factors; TREATMENT effectiveness; PEMPHIGUS; GENITOURINARY diseases; HYPERPIGMENTATION
- Publication
Dermatology Reports, 2023, Vol 15, Issue 3, p1
- ISSN
2036-7406
- Publication type
Article
- DOI
10.4081/dr.2023.9658