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- Title
Burden of Aquagenic Pruritus in Polycythaemia Vera.
- Authors
LELONEK, Edyta; MATUSIAK, Łukasz; WRÓBEL, Tomasz; KWIATKOWSKI, Jacek; SZEPIETOWSKI, Jacek C.
- Abstract
Aquagenic pruritus (AP) has a significant influence on quality of life (QoL) in patients with polycythaemia vera. This study analysed the impact of AP on patient well-being in 102 patients with polycythaemia vera. Intensity of pruritus was evaluated using a visual analogue scale (VAS), verbal rating scale (VRS) and a 4-item Itch Questionnaire. Psychosocial aspects of AP were assessed with the Hospital Anxiety and Depression Scale (HADS), EQ-5D and itch-specific QoL questionnaire (ItchyQoL). AP of mean duration 6.6 ± 8.6 years and intensity 4.8 ± 1.9 points (VAS) was present in 42/102 individuals. The prevalence of depression and anxiety among patients with AP was 23.8% and 9.5%, respectively. Depression was more frequent in the AP group (vs. non-AP). Moreover, patients with AP had higher HADSanxiety scoring than those without pruritus (p = 0.005). A negative correlation was found between duration of AP and EQ-5D-VAS. The ItchyQol score of 37.3 ± 12.3 points was influenced by the extent (p =0.01) and duration of episodes of AP (p = 0.02). In conclusion, AP places an additional burden on patients with polycythaemia vera, negatively influencing their QoL.
- Subjects
ITCHING; QUALITY of life; POLYCYTHEMIA vera; PSYCHOSOCIAL factors; ANXIETY; MENTAL depression; PATIENTS
- Publication
Acta Dermato-Venereologica, 2018, Vol 98, Issue 2, p185
- ISSN
0001-5555
- Publication type
Article
- DOI
10.2340/00015555-2812