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- Title
Post-Polio Syndrome Revisited.
- Authors
Punsoni, Michael; Lakis, Nelli S.; Mellion, Michelle; de la Monte, Suzanne M.
- Abstract
Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis. PPS afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), due to its selective impairment, degeneration, or death of motor neurons in the brainstem and spinal cord. Herein, we report a case of PPS in a 68-year-old man with a remote history of bulbar and cervical cord involvement by poliomyelitis, review the relevant literature, and contrast the salient histopathologic features that distinguish our case of PPS from ALS.
- Subjects
MOTOR neuron diseases; POSTPOLIOMYELITIS syndrome; AMYOTROPHIC lateral sclerosis; SYMPTOMS; SPINAL cord; MOTOR neurons
- Publication
Neurology International, 2023, Vol 15, Issue 2, p569
- ISSN
2035-8377
- Publication type
Article
- DOI
10.3390/neurolint15020035