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- Title
Pharmacogenomic testing: aiding in the management of psychotropic therapy for adolescents with autism spectrum disorders.
- Authors
Bose-Brill, Seuli; Jinming Xing; Barnette, Debra J.; Hanks, Christopher
- Abstract
Adolescents with autism have higher rates of anxiety than the general adolescent population. They often struggle to express psychological symptoms verbally where their symptoms may manifest as withdrawal and agitation. Adolescent patients with autism have higher rates of polypharmacy and high-risk psychiatric medication use (eg, atypical antipsychotics) than other patients with psychiatric illness. Primary care pediatricians are at the front lines of psychiatric management for patients with autism. Yet, they have inadequate access to pediatric psychiatry for complex medication management. Pharmacogenomic testing can provide personalized drug metabolism profiles for a majority of psychotropic medications. Primary care based pharmacogenomic testing for adolescents with autism on one or more psychiatric medications may help individualize and optimize complex medication regimens, while promoting drug safety.
- Subjects
TREATMENT of developmental disabilities; AUTISM spectrum disorders; PSYCHIATRIC drugs; PHARMACOGENOMICS; ADOLESCENT health; INDIVIDUALIZED medicine
- Publication
Pharmacogenomics & Personalized Medicine, 2017, Vol 10, p247
- ISSN
1178-7066
- Publication type
Article
- DOI
10.2147/PGPM.S130247