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- Title
Green synthesis of garlic oil-mediated selenium nanoparticles and its antimicrobial and cytotoxic activity.
- Authors
Anchana, R. Saishree; Arivarasu, Lakshminarayanan; Rajeshkumar, S.
- Abstract
Introduction: Nanoparticles, or matter ranging between 1 and 100 nm size, are of immense value in today's technological ventures, in all fields. Besides, if made of biodegradable materials, the preparation supports sustained drug release for a long time. Green chemistry is thus incorporated in nanotechnology. This study involves the synthesis of selenium nanoparticles (SeNP) incorporating garlic oil. Garlic is already known for its medicinal properties, of which its antimicrobial and cytotoxic nature will be studied. Aim: This study aims to evaluate the antimicrobial and cytotoxic activity of garlic oil-mediated SeNP. Methodology: Preparation of garlic oil incorporated SeNP was followed by a test for its antimicrobial activity using agar well diffusion method and cytotoxicity, using brine shrimps. Results: Garlic oil-mediated SeNP exhibits significant antimicrobial and cytotoxic activity. Conclusion: From the present study, it can be concluded that garlic oil-mediated SeNP have a good antimicrobial and cytotoxic activity at high concentrations.
- Subjects
GARLIC; ARTEMIA; SELENIUM; BIODEGRADABLE materials; SUSTAINABLE chemistry; ANTINEOPLASTIC antibiotics
- Publication
Drug Invention Today, 2020, Vol 14, Issue 2, p224
- ISSN
0975-7619
- Publication type
Article