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- Title
A review on role of Vitamin E supplementation in type 2 diabetes mellitus.
- Authors
Pavithra, D.; Praveen, D.; Chowdary, P. Ranadheer; Aanandhi, M. Vijey
- Abstract
Diabetes is a group of metabolic diseases characterized by hyperglycemia that is increased blood sugar level, resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, including eyes, kidneys, nerves, heart, and blood vessels. Vitamin E has antioxidant activity. It may also have antiatherogenic, antithrombotic, anticoagulant, neuroprotective, antiviral, immunomodulatory, cell membrane stabilizing, and antiproliferative actions. Vitamin E is a collective term used to describe eight separate forms, the best-known form being alpha-tocopherol. Vitamin E is a fat-soluble vitamin and is an important antioxidant. It acts to protect cells against the effects of free radicals, which are potentially damaging by-products of the body's metabolism. Antioxidants such as Vitamin E help protect against the damaging effects of free radicals, which may contribute to the development of chronic diseases such as cancer, complications in DM. It also protects other fat-soluble Vitamins (A and B group vitamins) from destruction by oxygen. Low levels of Vitamin E have been linked to increased incidence of long-time complications in DM. A comprehensive literature search has been carried out in PubMed and Google Scholar, and articles pertaining to complications of intravenous drug use were selected for review.
- Subjects
VITAMIN E; TYPE 2 diabetes treatment; BLOOD sugar; ANTIOXIDANTS; FIBRINOLYTIC agents
- Publication
Drug Invention Today, 2018, Vol 10, Issue 2, p236
- ISSN
0975-7619
- Publication type
Article