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- Title
Genomic Characterization of Methicillin-Susceptible Staphylococcus aureus Carriage in Patients on Home Parenteral Nutrition and Their Caregivers.
- Authors
Gompelman, Michelle; Weerdenburg, Ingrid J M van; Wezendonk, Guus T J; Coolen, Jordy P M; Akkermans, Reinier P; Rovers, Chantal P; Wertheim, Heiman F L; Wanten, Geert J A
- Abstract
In this prospective study, patients on home parenteral nutrition were twice as likely to be colonized with Staphylococcus aureus if their caregivers were carriers. Among S. aureus -positive patients and their caregivers, molecular analysis showed 68% genetically related strains. Despite decolonization, genetically related strains reappeared in 70% of patients.
- Subjects
CARRIER state (Communicable diseases); HOME care services; RISK assessment; GENOMICS; STAPHYLOCOCCAL diseases; PARENTERAL feeding; RESEARCH funding; LOGISTIC regression analysis; BACTEREMIA; SCIENTIFIC observation; SAMPLE size (Statistics); STAPHYLOCOCCUS aureus; METHICILLIN-resistant staphylococcus aureus; DESCRIPTIVE statistics; CAREGIVERS; DECOLONIZATION; LONGITUDINAL method; ODDS ratio; CONFIDENCE intervals; NUTRITION; GENETICS; DISEASE risk factors
- Publication
Clinical Infectious Diseases, 2024, Vol 78, Issue 5, p1285
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciad721