Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion.

Jing Wu; Yi Han; Ling Yang; Zhaoping Liu

This study attempted to investigate the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on painless induced abortion. A total of 82 pregnant females were divided into study group and reference group. The subjects in the study group took seaweed polysaccharides orally before surgery and received intravenous anesthesia with dexmedetomidine and propofol, while the subjects in the reference group received intravenous anesthesia with sufentanil combined with propofol. The onset time of anesthesia in the reference group was significantly shorter than that in the study group (P<0.001) and both recovery time and the dosage of propofol in the study group were significantly lower than those in the reference group (P<0.001). The values of MAP and HR at T3 and T4, clinical analgesia effective rate, ramsay sedation scores and incidence of adverse reactions of the subjects in study group was significantly better than those indexes of the subjects in reference group (P<0.05). The intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides is a promising strategy for painless induced abortion, which is worthy of application and popularization in clinical practice.

ABORTION; PROPOFOL; POLYSACCHARIDES; DEXMEDETOMIDINE; HEMODYNAMICS; PATIENT-controlled analgesia; INTRAVENOUS anesthesia

Pakistan Journal of Pharmaceutical Sciences, 2021, Vol 34, p1249

1011-601X

Academic Journal

10.36721/PJPS.2021.34.3.SP.1249-1254.1