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Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease.
- Published in:
- NPJ Parkinson's Disease, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41531-017-0032-2
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- Publication type:
- Article
PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.661505
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- Publication type:
- Article
Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson's Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 18, p. N.PAG, doi. 10.3390/ijms231810808
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- Publication type:
- Article
Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes.
- Published in:
- Glia, 2018, v. 66, n. 10, p. 2137, doi. 10.1002/glia.23467
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- Publication type:
- Article
Identification of Quantitative Trait Loci Across Recombinant Inbred Lines and Testcross Populations for Traits of Agronomic Importance in Rice.
- Published in:
- Genetics, 2006, v. 172, n. 2, p. 1287, doi. 10.1534/genetics.105.047209
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- Publication type:
- Article
Disruption of lipid rafts impairs the production of nitric oxide in lipopolysaccharide-stimulated murine RAW264.7 macrophages.
- Published in:
- Research on Chemical Intermediates, 2006, v. 32, n. 9, p. 847, doi. 10.1163/156856706778938455
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- Publication type:
- Article
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein.
- Published in:
- Science Signaling, 2019, v. 12, n. 572, p. N.PAG, doi. 10.1126/scisignal.aau4543
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- Publication type:
- Article
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells.
- Published in:
- Science Signaling, 2019, v. 12, n. 563, p. N.PAG, doi. 10.1126/scisignal.aat9900
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- Publication type:
- Article
The combination of dendritic cells-cytotoxic T lymphocytes/cytokine-induced killer (DC-CTL/CIK) therapy exerts immune and clinical responses in patients with malignant tumors.
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- Experimental Hematology & Oncology, 2015, p. 1, doi. 10.1186/s40164-015-0027-9
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- Publication type:
- Article
Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.631375
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- Publication type:
- Article
Protein Kinase D1 (PKD1) Phosphorylation Promotes Dopaminergic Neuronal Survival during 6-OHDA-Induced Oxidative Stress.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096947
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- Publication type:
- Article
Establishment of Mouse Teratocarcinomas Stem Cells Line and Screening Genes Responsible for Malignancy.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043955
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- Publication type:
- Article
Use of MicroRNA Let-7 to Control the Replication Specificity of Oncolytic Adenovirus in Hepatocellular Carcinoma Cells.
- Published in:
- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0021307
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- Publication type:
- Article
Chronic Manganese Exposure and the Enteric Nervous System: An in Vitro and Mouse in Vivo Study.
- Published in:
- Environmental Health Perspectives, 2021, v. 129, n. 8, p. 1, doi. 10.1289/EHP7877
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- Publication type:
- Article
Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation.
- Published in:
- Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1052925
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- Publication type:
- Article
Alterations in cytosine methylation and species-specific transcription induced by interspecific hybridization between Oryza sativa and O. officinalis.
- Published in:
- Theoretical & Applied Genetics, 2008, v. 117, n. 8, p. 1271, doi. 10.1007/s00122-008-0861-9
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- Publication type:
- Article
Emerging Microbiome Genetic Engineering Technology for Stable Levodopa Delivery in Parkinson's Disease.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R6272
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- Publication type:
- Article
Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease (1055.7).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1055.7
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- Publication type:
- Article
Hepcidin plays a key role in 6‐OHDA induced iron overload and apoptotic cell death in a cell culture model of Parkinson's disease (1038.2).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1038.2
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- Publication type:
- Article
Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease.
- Published in:
- 2020
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- Publication type:
- journal article
Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration.
- Published in:
- Nature Communications, 2016, v. 7, n. 10, p. 12932, doi. 10.1038/ncomms12932
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- Publication type:
- Article
Infusion of human umbilical cord-derived mesenchymal stem cells effectively relieves liver cirrhosis in DEN-induced rats.
- Published in:
- Molecular Medicine Reports, 2014, v. 9, n. 4, p. 1103, doi. 10.3892/mmr.2014.1927
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- Publication type:
- Article
Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease.
- Published in:
- Journal of Neurochemistry, 2017, v. 141, n. 5, p. 766, doi. 10.1111/jnc.14033
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- Publication type:
- Article
Molecular cloning, epigenetic regulation, and functional characterization of Prkd1 gene promoter in dopaminergic cell culture models of Parkinson's disease.
- Published in:
- Journal of Neurochemistry, 2015, v. 135, n. 2, p. 402, doi. 10.1111/jnc.13261
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- Publication type:
- Article
Correction: Modified CAR T cells targeting membrane-proximal epitope of mesothelin enhances the antitumor function against large solid tumor.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Modified CAR T cells targeting membrane-proximal epitope of mesothelin enhances the antitumor function against large solid tumor.
- Published in:
- Cell Death & Disease, 2019, v. 10, n. 7, p. N.PAG, doi. 10.1038/s41419-019-1711-1
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- Publication type:
- Article
Wnt/beta-catenin signaling in embryonic stem cell converted tumor cells.
- Published in:
- Journal of Translational Medicine, 2012, v. 10, n. 1, p. 196, doi. 10.1186/1479-5876-10-196
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- Publication type:
- Article
Blinded RT‐QuIC Analysis of α‐Synuclein Biomarker in Skin Tissue From Parkinson's Disease Patients.
- Published in:
- Movement Disorders, 2020, v. 35, n. 12, p. 2230, doi. 10.1002/mds.28242
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- Publication type:
- Article
α-Synuclein real-time quaking-induced conversion in the submandibular glands of Parkinson's disease patients.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson's Disease.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 8, p. 1831, doi. 10.3390/cells9081831
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- Publication type:
- Article
Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation.
- Published in:
- Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00654
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- Publication type:
- Article
Utilization of the CRISPR-Cas9 Gene Editing System to Dissect Neuroinflammatory and Neuropharmacological Mechanisms in Parkinson's Disease.
- Published in:
- Journal of NeuroImmune Pharmacology, 2019, v. 14, n. 4, p. 595, doi. 10.1007/s11481-019-09844-3
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- Publication type:
- Article
Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-Throughput Neuroimmune Biomarker Assay for Parkinsonian Disorders.
- Published in:
- Journal of NeuroImmune Pharmacology, 2019, v. 14, n. 3, p. 423, doi. 10.1007/s11481-019-09835-4
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- Publication type:
- Article
Involvement of c-Abl Kinase in Microglial Activation of NLRP3 Inflammasome and Impairment in Autolysosomal System.
- Published in:
- Journal of NeuroImmune Pharmacology, 2017, v. 12, n. 4, p. 624, doi. 10.1007/s11481-017-9746-5
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- Publication type:
- Article
Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson's Disease.
- Published in:
- Journal of NeuroImmune Pharmacology, 2016, v. 11, n. 2, p. 259, doi. 10.1007/s11481-016-9650-4
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- Publication type:
- Article
Production and characterization of a complete set of individual chromosome additions from Oryza officinalis to Oryza sativa using RFLP and GISH analyses.
- Published in:
- Theoretical & Applied Genetics, 2005, v. 111, n. 8, p. 1585, doi. 10.1007/s00122-005-0090-4
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- Publication type:
- Article
Simple sequence repeat analyses of interspecific hybrids and MAALs of Oryza officinalis and Oryza sativa.
- Published in:
- Genetica, 2008, v. 134, n. 2, p. 169, doi. 10.1007/s10709-007-9222-x
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- Publication type:
- Article
Hepcidin Plays a Key Role in 6-OHDA Induced Iron Overload and Apoptotic Cell Death in a Cell Culture Model of Parkinson’s Disease.
- Published in:
- Parkinson's Disease (20420080), 2016, p. 1, doi. 10.1155/2016/8684130
- By:
- Publication type:
- Article
N-Acetyl Cysteine Protects against Methamphetamine-Induced Dopaminergic Neurodegeneration via Modulation of Redox Status and Autophagy in Dopaminergic Cells.
- Published in:
- 2012
- By:
- Publication type:
- Journal Article
N-Acetyl Cysteine Protects against Methamphetamine-Induced Dopaminergic Neurodegeneration via Modulation of Redox Status and Autophagy in Dopaminergic Cells.
- Published in:
- Parkinson's Disease (20420080), 2012, p. 1, doi. 10.1155/2012/424285
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- Publication type:
- Article
Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease.
- Published in:
- Frontiers in Neuroscience, 2024, p. 01, doi. 10.3389/fnins.2024.1356703
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- Publication type:
- Article
High-Yield α-Synuclein Purification and Ionic Strength Modification Pivotal to Seed Amplification Assay Performance and Reproducibility.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 5988, doi. 10.3390/ijms25115988
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- Publication type:
- Article
Manganese and Vanadium Co-Exposure Induces Severe Neurotoxicity in the Olfactory System: Relevance to Metal-Induced Parkinsonism.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5285, doi. 10.3390/ijms25105285
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- Publication type:
- Article
Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity.
- Published in:
- Toxicological Sciences, 2019, v. 169, n. 2, p. 333, doi. 10.1093/toxsci/kfz049
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- Publication type:
- Article
α-Synuclein Protects Against Manganese Neurotoxic Insult During the Early Stages of Exposure in a Dopaminergic Cell Model of Parkinson’s Disease.
- Published in:
- Toxicological Sciences, 2015, v. 143, n. 2, p. 454, doi. 10.1093/toxsci/kfu247
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- Publication type:
- Article
Mitochondrial stress-induced H4K12 hyperacetylation dysregulates transcription in Parkinson’s disease.
- Published in:
- Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1422362
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- Publication type:
- Article
Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders.
- Published in:
- Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.836605
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- Publication type:
- Article
Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 27, p. 10058, doi. 10.1523/JNEUROSCI.0302-15.2015
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- Publication type:
- Article
α-Synuclein Negatively Regulates Protein Kinase Cδ Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 6, p. 2035, doi. 10.1523/JNEUROSCI.5634-10.2011
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- Publication type:
- Article
IL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer.
- Published in:
- BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03420-0
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- Publication type:
- Article