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- Title
The effect of exercise training on serum Omentin-1 levels, glycemic control and body composition in adults population: a systematic review and meta-analysis of randomized controlled trials.
- Authors
Asgari, Ali; Niyazi, Arghavan; Nejatian Hoseinpour, Ali; Setayesh, Shayan; Fazolahzade Mousavi, Rokhsare; Mohammad Rahimi, Gholam Rasul
- Abstract
Background: Omentin-1 has been acknowledged as an anti-inflammatory and insulin-sensitizing marker, which is mainly expressed in adipose tissue. Exercise training is a therapeutic intervention that can possibly improve and modify circulating Omentin-1 levels. Objective: To determine the effects of exercise training on circulating Omentin-1, glycemic control, and body composition in adult population. Data sources: Four electronic databases and reference lists of included articles were searched until February 5, 2023. The effect size of outcomes was summarized by calculating the mean difference (MD) with 95% confidence interval (CI). Results: Ten RCTs comprising 385 participants were included. The overall model revealed that exercise training increased Omentin-1 compared to the control (MD = 3.57 ng.ml; 95% CI, 1.80 to 5.34 ng.ml; p < 0.001). Subgroup analysis by exercise modalities revealed significant increases in Omentin-1 after isolated aerobic (p = 0.002) and resistance (p < 0.001) training but not after combined training. Subgroup analysis by sex indicated a significant improvement of Omentin-1 in women (p = 0.015) and men (p = 0.007). Furthermore, a significant increase was found in both healthy (p = 0.035) and non-healthy (p = 0.002) participants. Analysis of other outcomes indicated that exercise training significantly reduced glucose, insulin, insulin resistance, body weight, body mass index, and body fat, as well as improved lipid profiles. Conclusion: These findings reveal that isolated aerobic and resistance exercises resulted in an increase in serum levels of Omentin-1 in adults. More high-quality studies are required to clarify the mechanisms underlying the influence of exercise training on Omentin-1 concentrations.
- Subjects
ADIPOKINES; BODY mass index; ADIPOSE tissues; EXERCISE therapy; GLYCEMIC control; BODY composition; BODY weight; LIPIDS; META-analysis; DESCRIPTIVE statistics; INSULIN; SYSTEMATIC reviews; MEDLINE; BLOOD sugar; INSULIN resistance; RESISTANCE training; AEROBIC exercises; ONLINE information services; CONFIDENCE intervals; BIOMARKERS
- Publication
International Journal of Diabetes in Developing Countries, 2024, Vol 44, Issue 3, p437
- ISSN
0973-3930
- Publication type
Article
- DOI
10.1007/s13410-023-01229-w