We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Whole-body diffusion-weighted imaging compared with FDG-PET/CT in staging of lymphoma patients.
- Authors
Abdulqadhr G; Molin D; Aström G; Suurküla M; Johansson L; Hagberg H; Ahlström H; Abdulqadhr, Goran; Molin, Daniel; Aström, Gunnar; Suurküla, Madis; Johansson, Lars; Hagberg, Hans; Ahlström, Håkan
- Abstract
<bold>Background: </bold>Diffusion-weighted imaging (DWI) has become increasingly valuable in lymph node imaging, yet the clinical utility of this technique in the staging of lymphoma has not been established. <bold>Purpose: </bold>To compare whole-body DWI with FDG-PET/CT in the staging of lymphoma patients. <bold>Material and Methods: </bold>Thirty-one patients, eight with Hodgkin lymphoma (HL) and 23 with non-Hodgkin's lymphoma (18 aggressive and five indolent) underwent both whole-body DWI, whole-body MRI (T1W and T2W-STIR) and FDG-PET/CT. Lesions on whole-body DWI were only considered positive if they correlated with lesions on T1W and T2W-STIR images. The staging given by each technique was compared, according to the Ann Arbor staging system. Differences in staging were solved using biopsy results, and clinical and CT follow-ups as standard of reference. <bold>Results: </bold>The staging was the same for DWI and FDG-PET/CT in 28 (90.3%) patients and different in three (9.7%). Of the 28 patients with the same staging, 11 had stage IV in both techniques and 17 had stages 0-III. No HL or aggressive non-Hodgkin's lymphoma patients had different staging. Three indolent small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) lymphoma had higher staging with DWI when compared with FDG-PET/CT. One small subcutaneous breast lymphoma was not seen but all other extranodal sites were detected by both techniques. <bold>Conclusion: </bold>Whole-body DWI is a promising technique for staging of both (aggressive and indolent) non-Hodgkin's lymphoma and HL.
- Subjects
MEDICAL research; HODGKIN'S disease; RETICULOENDOTHELIAL granulomas; LYMPHOPROLIFERATIVE disorders; LYMPHOCYTIC leukemia; MEDICAL imaging systems
- Publication
Acta Radiologica, 2011, Vol 52, Issue 2, p173
- ISSN
0284-1851
- Publication type
journal article
- DOI
10.1258/ar.2010.100246