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- Title
Eco-Friendly Multi-Component Synthesis of γ-Spiroiminolactones in Water.
- Authors
Safaei, Hamid Reza; Shekouhy, Mohsen
- Abstract
γ-Spiroiminolactone derivatives can be synthesized through an one-pot three-component reaction of cyclic carbonyl compounds (isatin, acenaphthoquinone, ninhydrin), activated α-methylene carbonyl groups and isocyanides in water using sodium dodecyl sulfate (SDS) as a commercially available and cheap surfactant compound. All products were obtained in good to excellent yields without formation of any by-products in water as a green and benign reaction medium. Moreover, presented method was successfully applied for the synthesis of some novel bis(spiroiminolactone) derivatives.
- Subjects
CHEMICAL reactions; HETEROCYCLIC compounds; SODIUM dodecyl sulfate; DICHLOROMETHANE; ISOCYANIDES
- Publication
Acta Chimica Slovenica, 2017, Vol 64, Issue 4, p1020
- ISSN
1318-0207
- Publication type
Article
- DOI
10.17344/acsi.2017.3773