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- Title
老年人群多重用药现状调查与分析.
- Authors
邓 敏; ,尹 畅; 吴含达; 王 雪; 拓西平; 周 全; 蔡全才; 陈礼治; 王 卓1,2,3.
- Abstract
OBJECTIVE: To investigate the common diseases, commonly used drugs and polypharmacy in the elderly, so as to provide basis for the formulation of drug rearrangement strategies in the elderly. METHODS: The oral drug information of local and military patients of three tertiary hospitals was collected, the drug information of retired officers living in sanatoriums in Shanghai was investigated by questionnaire survey method, and the disease and medication of outpatients and retired officers were analyzed. RESULTS: A total of 15 356 patients were enrolled in the analysis, including 459 local patients in hospital A, 598 local patients in hospital B, 13 213 local patients in hospital C, 366 military patients in hospital C, and 720 retired officers in sanatoriums. The mean age (84. 55±10. 09) years, the mean number of diseases (5. 78±3. 34) categories, and the mean number of drugs (6. 43±3. 80) categories of retired officers in sanatoriums were higher than those of other elderly patients, with statistically significant differences (P<0. 01). Among local patients in hospital A, local patients in hospital B, local patients in hospital C, military patients in hospital C, and anretired officers in sanatoriums, those taking 5 or more drugs accounted for 6. 32%(29 / 459), 10. 37% (62 / 598), 13. 04% (1 723 / 13 213), 60. 93% (223 / 366) and 68. 61% (494 / 720). In addition to the old cadres under the age of 70, the prevalence of polypharmacy in retired officers with other different characteristics were more than >50%,and the polypharmacy was remarkably serious among the elderly with older age, lower education and worse sleep quality. Retired officers were mainly suffering from chronic diseases, and the mean number of medications used by patients in different disease groups and drug groups with various drugs was more than 7. Except for the osteoporosis disease group (56. 04%, 181 / 323), the prevalence of polypharmacy used by patients in other groups was > 70%, and the phenomenon of polypharmacy was prevalent for each common chronic disease and its commonly used therapeutic drugs. CONCLUSIONS: The prevalence of comorbidity and polypharmacy in the elderly is serious, and outpatient prescription intervention cannot effectively solve the problem of polypharmacy, and it is necessary to formulate the medication reconciliation strategy suitable for the elderly.
- Subjects
SHANGHAI (China); OLDER patients; SLEEP quality; MEDICATION reconciliation; HOSPITAL patients; MILITARY hospitals; ORAL medication; ORAL examinations (Education)
- Publication
Evaluation & Analysis of Drug-Use in Hospitals of China, 2022, Vol 22, Issue 10, p1251
- ISSN
1672-2124
- Publication type
Article
- DOI
10.14009/j.issn.1672-2124.2022.10.021