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- Title
睾丸穿刺取精与经皮附睾取精行卵细胞浆内 单精子注射技术的 meta 分析.
- Authors
李丹; 杨旭; 张唯力; 胡丽娜; 张荣贵
- Abstract
Objective To compare the efficiency of testicular sperm aspiration and percutaneous epididymal sperm aspiration for receiving intracytoplasmic sperm injection(ICSI) assisted reproduction. Methods PubMed, EMBASE, Cochrane Library, CNKI, Wanfang database and VIP database were searched, and all publications before October 2017 which related to comparing testicular sperm aspiration and percutaneous epididymal sperm aspiration for ICSI were browsed. According to the inclusion and exclusion criteria, the literature was screened and the data were extracted. The Newcastle-Ottawa Scale (NOS) was recommended for quality e-valuation of non-randomized studies, and Rev Man 5.3 was used for meta-analysis. Results A total of 20 literatures were recruited, including 1 464 cycles and 2 526 cycles used sperm by testicular sperm aspiration and percutaneous epididymal sperm aspiration for ICSI, respectively. The results based on meta-analysis showed that no significant differences could be observed between groups u-sing testicular sperm aspiration and percutaneous epididymal sperm aspiration in rates of pregnancy (RR= 1.06, 95%CI 0.99 — 1.13, P = 0.11), abortion (RR = 0.99,95%CI 0.76-1.30, P = 0.97), live birth (RR = 0.99, 95%CI 0.86-1.14, P = 0.88), ectopic pregnancy (RR= 1.44,95%CI 0.70 — 2.95, P = 0.32). deformity (RR = 1.71,95% CI 0.50 — 5.80, P = 0.39), singleton (RR = 0.95, 95%CI 0.85—1.06.P = 0.38), multiple pregnancy (RR= 1.12, 95%CI 0.90 — 1.39,P = 0.32), respectively. In addition, no severe complications, such as postoperative infection, scrotal hematoma or sexual dysfunction, were reported between two groups. Conclusion Testicular sperm aspiration and percutaneous epididymal sperm aspiration would be similarly safe and efficient for patients receiving ICSI assisted reproduction.
- Publication
Journal of Modern Medicine & Health, 2019, Vol 35, Issue 4, p505
- ISSN
1009-5519
- Publication type
Article
- DOI
10.3969/j.issn.1009-5519.2019.04.007