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- Title
Does Exposure to Stressors Predict Changes in Physiological Dysregulation?
- Authors
Glei, Dana; Goldman, Noreen; Wu, Chih-Hsun; Weinstein, Maxine
- Abstract
Background: The allostatic load framework implies that cumulative exposure to stressors results in multi-system physiological dysregulation. Purpose: The purpose of this study was to investigate the effect of stress burden on subsequent changes (2000-2006) in physiological dysregulation. Methods: Data came from a population-based cohort study in Taiwan ( n = 521, aged 54+ in 2000, re-examined in 2006). Measures of stressful events and chronic strain were based on questions asked in 1996, 1999, and 2000. A measure of trauma was based on exposure to the 1999 earthquake. Dysregulation was based on 17 biomarkers (e.g., metabolic, inflammatory, neuroendocrine). Results: There were some small effects among men: chronic strain was associated with subsequent increases in dysregulation (standardized β = 0.08, 95 % CI = 0.01 to 0.20), particularly inflammation; life events were also associated with increased inflammation ( β = 0.10, CI = 0.01 to 0.26). There were no significant effects in women. Conclusions: We found weak evidence that stress burden is associated with changes in dysregulation.
- Subjects
PHYSIOLOGICAL stress; LIFE change events; CLINICAL health psychology; COHORT analysis; PHYSIOLOGIC strain
- Publication
Annals of Behavioral Medicine, 2013, Vol 46, Issue 1, p121
- ISSN
0883-6612
- Publication type
Report
- DOI
10.1007/s12160-013-9485-7