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- Title
Impedance characteristics of esophageal motor function in achalasia.
- Authors
Nguyen, H. N.; Domingues, G. R.; Winograd, R.; Lammert, E.; Silny, J.; Matern, S.
- Abstract
Detailed data on patterns of esophageal bolus transport in patients with achalasia are still lacking. To study these we applied the novel technique of multichannel intraluminal impedance measurements. Ten patients with achalasia were studied using a 16 channel system. Liquid and semisolid boluses of 10 mL were applied with the patients in a supine position. Patterns of bolus transport were determined and analyzed as compared to results obtained from 20 healthy subjects. The healthy subjects featured a unique typical primary peristalsis pattern independent of bolus viscosity. In contrast, achalasia patients demonstrated different impedance characteristics, including: (i) significantly lower baseline esophageal impedance during the resting state as compared with healthy volunteers (999 &Ohm; ± 108 versus 2749 &Ohm; ± 113); (ii) failed bolus transport through the esophagus in all cases; (iii) impedance evidence of luminal content regurgitation in 35% of the swallows (iv) impedance evidence of pathological air movement within the proximal esophagus during deglutition in 38% of the swallows, so called air trapping. Thus, impedance characteristics of achalasia have been defined and can be attributed to known symptoms of achalasia. They can be used as basic findings for further classification of pathological bolus transports in other esophageal motility disorders.
- Subjects
ESOPHAGEAL motility disorders; MUSCLE contraction; GASTROINTESTINAL motility; SUPINE position; SLEEP positions; ALIMENTARY canal
- Publication
Diseases of the Esophagus, 2004, Vol 17, Issue 1, p44
- ISSN
1120-8694
- Publication type
Article
- DOI
10.1111/j.1442-2050.2004.00372.x