We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
"Disappointing" Trial Results Offer Hope for Older Women With Breast Cancer.
- Authors
Voelker, Rebecca
- Abstract
The article reveals that the phase 3 trials of adjuvant bisphosphonate therapy in women with breast cancer has generated a new hypothesis that it may improve survival odds and the risk of disease progression in women with low estrogen levels from natural menopause or medication-induced ovarian suppression. It was found by the Austrian Breast and Colorectal Cancer Study Group trial 12 that the addition of zoledronic acid to adjuvant hormone therapy for 3 years reduced the risk of disease progression by 36%. The implications of the findings for medical practice are explored.
- Subjects
DIPHOSPHONATES; HORMONE therapy for menopause; HORMONE therapy; ESTROGEN replacement therapy; PHOSPHONATES; DISODIUM pamidronate; THERAPEUTICS
- Publication
JAMA: Journal of the American Medical Association, 2011, Vol 305, Issue 8, p765
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2011.172