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- Title
A Robot-Assisted Cell Manipulation System with an Adaptive Visual Servoing Method.
- Authors
Yu Xie; Feng Zeng; Wenming Xi; Yunlei Zhou; Houde Liu; Mingliang Chen
- Abstract
Robot-assisted cell manipulation is gaining attention for its ability in providing high throughput and high precision cell manipulation for the biological industry. This paper presents a visual servo microrobotic system for cell microinjection. We investigated the automatic cell autofocus method that reduced the complexity of the system. Then, we produced an adaptive visual processing algorithm to detect the location of the cell and micropipette toward the uneven illumination problem. Fourteen microinjection experiments were conducted with zebrafish embryos. A 100% success rate was achieved either in autofocus or embryo detection, which verified the robustness of the proposed automatic cell manipulation system.
- Subjects
ROBOTS; CELLS; MICROINJECTION (Cytology)
- Publication
Micromachines, 2016, Vol 7, Issue 6, p104
- ISSN
2072-666X
- Publication type
Article
- DOI
10.3390/mi7060104