We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review.
- Authors
Sadeghi, Fatemeh; Mockler, David; Guinan, Emer M.; Hussey, Juliette; Doyle, Suzanne L.
- Abstract
Malnutrition and muscle wasting are associated with impaired physical functioning and quality of life in oncology patients. Patients diagnosed with upper gastrointestinal (GI) cancers are considered at high risk of malnutrition and impaired function. Due to continuous improvement in upper GI cancer survival rates, there has been an increased focus on multimodal interventions aimed at minimizing the adverse effects of cancer treatments and enhancing survivors' quality of life. The present study aimed to evaluate the effectiveness of combined nutritional and exercise interventions in improving muscle wasting, physical functioning, and quality of life in patients with upper GI cancer. A comprehensive search was conducted in MEDLINE, EMBASE, Web of Science, Cochrane Library, and CINHAL. Of the 4780 identified articles, 148 were selected for full-text review, of which 5 studies met the inclusion criteria. Whilst reviewed studies showed promising effects of multimodal interventions on physical functioning, no significant differences in postoperative complications and hospital stay were observed. Limited available evidence showed conflicting results regarding the effectiveness of these interventions on preserving muscle mass and improving health-related quality of life. Further studies examining the impact of nutrition and exercise interventions on upper GI patient outcomes are required and would benefit from reporting a core outcome set.
- Subjects
GASTROINTESTINAL tumors treatment; MUSCULAR atrophy; CINAHL database; MEDICAL information storage &; retrieval systems; MEDICAL databases; INFORMATION storage &; retrieval systems; NUTRITION; FUNCTIONAL status; SYSTEMATIC reviews; TREATMENT effectiveness; QUALITY of life; MEDLINE; EXERCISE therapy
- Publication
Nutrients, 2021, Vol 13, Issue 8, p2842
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu13082842