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- Title
Sensibilidad diagnóstica de variables antropométricas y bioquímicas empleando los índices HOMA-IR y QUICKI, para la determinación de resistencia a la insulina en un grupo de escolares obesos prepúberes.
- Authors
Alba Mariana, Herrera; Dora, González; Nerkis, Angulo; Edgar, Acosta
- Abstract
Obesity in childhood has been associated with a high probability of obesity in adulthood. Therefore, it has been seen as a public health problem affecting the life of the individual from childhood to adulthood. Therefore, the objective of the present study was to evaluate insulin resistance and sensitivity through the HOMA-IR and QUICKI indices in obese prepuber schoolchildren, to correlate them with the anthropometric and biochemical variables; and to determine the diagnostic sensitivity of the variables using both indices as reference. We evaluated 181 schoolchildren (6-11 years), in two groups: eutrophic group (90 children) and obese group (91 children); with sexual maturation tanner I and II. The HOMA-IR and QUICKI values were determined for both populations, and the obese group had higher HOMA-IR and QUICKI values (3.40 (11.5) and 0.32 (0.11) respectively. As for the correlation; there was a significant difference in BMI, WC, GA, glucose, insulin and triglycerides (TG) with both indices. In addition to this, BMI, WC, insulin, TG and the TG/C-HDL ratio; demonstrated good diagnostic sensitivity using HOMA-IR as a reference. In conclusion, both indices have a good correlation and predictive capacity, detecting the presence of IR and SI decreased in the studied group..
- Subjects
CHILDHOOD obesity; INSULIN resistance; SCHOOL children; OBESITY; ADULTS
- Publication
Salus Online, 2018, Vol 22, Issue 2, p21
- ISSN
1316-7138
- Publication type
Article