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- Title
Evaluation of Bone Metabolism Biomarkers in Hemodialysis Chronic Kidney Disease.
- Authors
Rija, Firas Faris; Mubarak Almahdawi, Zaid Mohmmed; Hussein, Sura Zahim
- Abstract
Metabolic bone disease (MBD) is a common complication of chronic kidney disease (CKD) and is a part of a broad spectrum of disorders of mineral metabolism that occur in this clinical setting and result in both skeletal and extraskletal consequences. This study was a cross sectional which conducted in Dialysis Unit in Tikrit Teaching Hospital in Tikrit city. The study started from January 2018 to August 2018 on study population age ranged from (18 - 68) years old The total of 60 subjects were separated to two groups as following: Control: This group consist of 30 healthy individuals (15 females and 15 males), and Hemodialysis (HD) (CKD) patients: This group consist of CKD 30 patients (15 females and 15 males). The results referred to the increased levels of Transforming growth factor-β (TGF-β), Osteoprogestrin (OPG), Sclerostin (SOST), Osteocalcin (OC) and C-reactive protein (CRP) in CKD with HD with highly significant differences (P≤0.01) when compared with control group. The bone metabolism biomarkers are increased in HD CKD patients who complicated to MBD.
- Publication
Indian Journal of Public Health Research & Development, 2019, Vol 10, Issue 4, p1660
- ISSN
0976-0245
- Publication type
Article
- DOI
10.5958/0976-5506.2019.00953.7