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- Title
Prognosis of Multifocal Papillary Thyroid Carcinoma.
- Authors
Sheng-Fong Kuo; Shu-Fu Lin; Tzu-Chieh Chao; Chuen Hsueh; Kun-Ju Lin; Jen-Der Lin
- Abstract
This study was to investigate the clinical features and therapeutic outcomes of multifocal papillary thyroid microcarcinoma (PTMC). A total of 2,418 papillary thyroid carcinoma (PTC) patients had undergone thyroidectomy in one medical center between 1977 and 2010. There were 483 (20.0%) diagnosed with multifocal PTC. The percentage of multifocal PTC was higher in PTMC patients (22.0%) than in non-PTMC patients (19.5%). Demographic and clinical characteristics of PTMC and multifocal PTC in PTC patients were traced. Multifocal PTC patients presented with smaller tumors at an older age, and a higher percentage underwent total or complete thyroidectomy. These patients also showed a higher incidence of postoperative disease progression than did unifocal PTC patients. Comparison of 483 patients with multifocal PTMC and non-PTMC tumors showed a higher incidence of postoperative disease progression in patients with non-PTMC; otherwise, there was no statistical difference in disease-specific and total mortality between these two groups. In conclusion, the incidence of multifocal PTMC was not lower than that of non-PTMC, and postoperative therapies were necessary for both multifocal PTMC and non-PTMC patients.
- Subjects
THYROID cancer treatment; PAPILLARY carcinoma; THYROID cancer; THYROIDECTOMY; HEALTH outcome assessment; POSTOPERATIVE care; PROGNOSIS
- Publication
International Journal of Endocrinology, 2013, p1
- ISSN
1687-8337
- Publication type
Article
- DOI
10.1155/2013/809382