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- Title
Hepatoprotective constituents of cudrania tricuspidata.
- Authors
Tian, Yu-Hua; Kim, Hyun-Chul; Cui, Jiong-Mo; Kim, Youn-Chul
- Abstract
Phytochemical investigation of the MeOH extract of the root barks of Cudrania tricuspidata Bureau (Moraceae), as guided by hepatoprotective activity in vitro, furnished four isoprenylated xanthones, cudratricusxanthone A ( 1), cudraxanthone L ( 2), cudratricusxanthone E ( 3), and macluraxanthone B ( 4). All of these compounds showed the significant hepatoprotective effect on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. Compounds 1, 2, and 4 also exhibited the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.
- Publication
Archives of Pharmacal Research, 2005, Vol 28, Issue 1, p44
- ISSN
0253-6269
- Publication type
Article
- DOI
10.1007/BF02975134