We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A randomized double-blind, placebo-controlled trial of the EMLA patch for the reduction of pain associated with intramuscular injection in four to six-year-old children.
- Authors
Cassidy, K L; Reid, G J; McGrath, P J; Smith, D J; Brown, T L; Finley, G A
- Abstract
<bold>Unlabelled: </bold>The effectiveness of a eutectic mixture lidocaine-prilocaine topical anaesthetic cream (EMLA) patch compared with a placebo patch in the reduction of pain associated with intramuscular immunization was evaluated. As part of the study, 161 children (aged 4-6-y) undergoing routine diphtheria, pertussis, tetanus and polio (DPTP) immunization in five urban and five rural private office settings were randomly assigned to an EMLA patch (n = 83) or a placebo patch control group (n = 78). Pain measurements included: child's self-report on a Faces Pain Scale; facial action on the Child Facial Coding System; the Children's Hospital of Eastern Ontario Pain Scale and parent and technician ratings on a Visual Analogue Scale. Parents also rated their own and their child's immunization-related anxiety on a Visual Analogue Scale. The EMLA patch group had significantly less pain on all four pain measures compared with the placebo group. Of the children in the placebo group, 43% had clinically significant pain, compared with 17% of children in the EMLA patch group. No severe adverse symptoms occurred as a result of either EMLA or placebo patch application.<bold>Conclusion: </bold>The EMLA patch reduced immunization pain in 4 to 6-y-old children during needle injection.
- Subjects
EMLA (Anesthetics); INTRAMUSCULAR injections
- Publication
Acta Paediatrica, 2001, Vol 90, Issue 11, p1329
- ISSN
0803-5253
- Publication type
journal article
- DOI
10.1080/080352501317130416