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- Title
Comparative Outcomes of Bariatric Surgery in Patients With and Without Human Immunodeficiency Virus.
- Authors
Sharma, Gautam; Strong, Andrew T.; Boules, Mena; Tu, Chao; Szomstein, Samuel; Rosenthal, Raul; Rodriguez, John; Taege, Alan J.; Kroh, Matthew
- Abstract
Background: Paradoxically, advances in anti-retroviral therapy that has increased survival for patients with human immunodeficiency virus (HIV) have resulted in greater numbers of HIV+ patients developing other chronic diseases, including obesity. Little comparative literature exists detailing perioperative or metabolic outcomes of bariatric surgery in the HIV+ population compared to HIV negative (HIV−) controls.Methods: This is a retrospective case-control study with both HIV+ (case) and HIV− control patients. Individuals undergoing sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) between January 1, 2006 and December 31, 2015 were included. HIV+ status was defined as any individual with documented history of HIV.Results: Eleven HIV+ patients underwent RYGB or SG during the study period. After matching (1:5 HIV+: HIV−) both cohorts had similar mean age (42 years), gender distribution (63% female), and preoperative BMI (48 kg/m2), as well as comorbidities. There were no differences in postoperative length of stay, or all cause 30-day morbidity. There were 63.7% HIV+ and 76.4% with 1-year follow-up available. Both percent excess weight loss (56% HIV+ vs. 60% HIV−) and BMI (32 HIV+ vs. 34 kg/m2 HIV−) were similar in both groups. There were minimal changes to CD4 count or HIV viral load in the patients during the follow-up period.Conclusion: Bariatric surgery is safe and feasible in HIV-infected population well controlled on anti-retroviral medication. The short-term surgical and metabolic outcomes are similar to HIV− controls with minimal effect on the CD4 count and viral load in HIV+ cohort for long-term follow-up.
- Subjects
HIV-positive persons; HIV; OBESITY risk factors; PHYSIOLOGY
- Publication
Obesity Surgery, 2018, Vol 28, Issue 4, p1070
- ISSN
0960-8923
- Publication type
Article
- DOI
10.1007/s11695-017-2996-8