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- Title
Prevalence of migraine, tension-type headache and trigeminal neuralgia in multiple sclerosis.
- Authors
Putzki, N.; Pfriem, A.; Limmroth, V.; Yaldizli, Ö.; Tettenborn, B.; Diener, H. C.; Katsarava, Z.
- Abstract
Background: Prevalence rates of headache in multiple sclerosis (MS) patients varied widely in recent studies. This study aimed to investigate the 1 year prevalence of headache in MS compared with the general population. Methods: Population-based case–control study in Germany. Results: We included 491 patients with definite MS (68% female, mean age 45.3 years, 63.7% relapsing remitting MS, mean Expanded Disability Status Scale (EDSS) 3.2, 106 treated with interferon-β, 53 with glatiramer acetate, 271 untreated) and 447 age and gender matched controls. Headache was diagnosed with a validated questionnaire according to the International Headache Society Criteria. Headache prevalence was 56.2% (tension type headache 37.2%, migraine 24.6%). Headache prevalence rates did not differ from controls. Headache was not associated with disability or treatment. Trigeminal neuralgia was found in 6.3% of MS cases. Conclusion: Results suggest that headache in MS patients reflects comorbidity in most conditions.
- Subjects
MULTIPLE sclerosis; HEADACHE; MIGRAINE; TRIGEMINAL neuralgia; DISEASE prevalence
- Publication
European Journal of Neurology, 2009, Vol 16, Issue 2, p262
- ISSN
1351-5101
- Publication type
Article
- DOI
10.1111/j.1468-1331.2008.02406.x