We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The integrin—growth factor receptor duet.
- Authors
Alam, Naved; Goel, Hira Lal; Zarif, Matthew J.; Butterfield, Julie E.; Perkins, Hillary M.; Sansoucy, Brian G.; Sawyer, Thomas K.; Languino, Lucia R.
- Abstract
Cell adhesion receptors, referred to as integrins, are recognized as key regulators of cellular processes including growth and differentiation. Integrins communicate with growth factor receptors (GFRs) to control specific cellular responses to stimuli originating in the extracellular environment. In this article, we review the role of integrins as molecular switches that modulate GFR activation and specificity. We also examine the reciprocal modulation of integrin functions by GFRs and the mechanisms through which those actions are fine-tuned. J. Cell. Physiol. 213:649–653. © 2007 Wiley-Liss, Inc.
- Subjects
GLYCOPROTEINS; CELL adhesion molecules; CELL adhesion; CELL communication; CYTOKINES; MEMBRANE fusion
- Publication
Journal of Cellular Physiology, 2007, Vol 213, Issue 3, p649
- ISSN
0021-9541
- Publication type
Article
- DOI
10.1002/jcp.21278