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The Tsc/Rheb signaling pathway controls basic amino acid uptake via the Cat1 permease in fission yeast.
- Published in:
- Molecular Genetics & Genomics, 2008, v. 279, n. 5, p. 441, doi. 10.1007/s00438-008-0320-y
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- Publication type:
- Article
Activating mutations of TOR (target of rapamycin).
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- Genes to Cells, 2011, v. 16, n. 2, p. 141, doi. 10.1111/j.1365-2443.2010.01482.x
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- Publication type:
- Article
Tumor Accumulation of PIP-Based KRAS Inhibitor KR12 Evaluated by the Use of a Simple, Versatile Chicken Egg Tumor Model.
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- Cancers, 2022, v. 14, n. 4, p. 951, doi. 10.3390/cancers14040951
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- Publication type:
- Article
In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells.
- Published in:
- BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-198
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- Publication type:
- Article
Two-Photon-Triggered Drug Delivery in Cancer Cells Using Nanoimpellers.
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- Angewandte Chemie International Edition, 2013, v. 52, n. 51, p. 13813, doi. 10.1002/anie.201308647
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- Publication type:
- Article
Tailoring the biodegradability of porous silicon nanoparticles.
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- Journal of Biomedical Materials Research, Part A, 2012, v. 100A, n. 12, p. 3416, doi. 10.1002/jbm.a.34294
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- Publication type:
- Article
Advances in the development of farnesyltransferase inhibitors: Substrate recognition by protein farnesyltransferase.
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- Journal of Cellular Biochemistry, 1997, v. 67, p. 12, doi. 10.1002/(SICI)1097-4644(1997)27+<12::AID-JCB5>3.0.CO;2-4
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- Article
The CAM Model for CIC-DUX4 Sarcoma and Its Potential Use for Precision Medicine.
- Published in:
- 2021
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- Publication type:
- Abstract
Patient Derived Chicken Egg Tumor Model (PDcE Model): Current Status and Critical Issues.
- Published in:
- Cells (2073-4409), 2019, v. 8, n. 5, p. 440, doi. 10.3390/cells8050440
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- Publication type:
- Article
An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation.
- Published in:
- 2018
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- Publication type:
- journal article
Systematic Identification of Cellular Signals Reactivating Kaposi Sarcoma-Associated Herpesvirus.
- Published in:
- PLoS Pathogens, 2007, v. 3, n. 3, p. 0444, doi. 10.1371/journal.ppat.0030044
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- Publication type:
- Article
Destruction of tumor mass by gadolinium-loaded nanoparticles irradiated with monochromatic X-rays: Implications for the Auger therapy.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49978-1
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- Publication type:
- Article
Studies on the Exposure of Gadolinium Containing Nanoparticles with Monochromatic X-rays Drive Advances in Radiation Therapy.
- Published in:
- Nanomaterials (2079-4991), 2020, v. 10, n. 7, p. 1341, doi. 10.3390/nano10071341
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- Publication type:
- Article
Identification of novel single amino acid changes that result in hyperactivation of the unique GTPase, Rheb, in fission yeast.
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- Molecular Microbiology, 2005, v. 58, n. 4, p. 1074, doi. 10.1111/j.1365-2958.2005.04877.x
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- Publication type:
- Article
Structure and expression of yeast DPR1, a gene essential for the processing and intracellular localiation of ras proteins.
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- Yeast, 1988, v. 4, n. 4, p. 271, doi. 10.1002/yea.320040405
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- Publication type:
- Article
Therapeutic intervention based on protein prenylation and associated modifications.
- Published in:
- Nature Chemical Biology, 2006, v. 2, n. 10, p. 518, doi. 10.1038/nchembio818
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- Publication type:
- Article
Failure to farnesylate Rheb protein contributes to the enrichment of G0/G1 phase cells in the Schizosaccharomyces pombe farnesyltransferase mutant.
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- Molecular Microbiology, 2001, v. 41, n. 6, p. 1339, doi. 10.1046/j.1365-2958.2001.02599.x
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- Publication type:
- Article
Characterization of the geranylgeranyl transferase type I from Schizosaccharomyces pombe.
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- Molecular Microbiology, 1998, v. 29, n. 6, p. 1357, doi. 10.1046/j.1365-2958.1998.01009.x
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- Publication type:
- Article
Functional Nanovalves on Protein-Coated Nanoparticles for In vitro and In vivo Controlled Drug Delivery.
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- Small, 2015, v. 11, n. 3, p. 319, doi. 10.1002/smll.201400765
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- Publication type:
- Article
Two-Photon-Triggered Drug Delivery via Fluorescent Nanovalves.
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- Small, 2014, v. 10, n. 9, p. 1752, doi. 10.1002/smll.201400042
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- Publication type:
- Article
mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33872-y
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- Publication type:
- Article
PAK1 Kinase Promotes Cell Motility and Invasiveness through CRK-II Serine Phosphorylation in Non-Small Cell Lung Cancer Cells.
- Published in:
- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0042012
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- Publication type:
- Article
Identification and Characterization of Mechanism of Action of P61-E7, a Novel Phosphine Catalysis-Based Inhibitor of Geranylgeranyltransferase-I.
- Published in:
- PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026135
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- Publication type:
- Article
Mesostructured Silica for Optical Functionality, Nanomachines, and Drug Delivery.
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- Journal of the American Ceramic Society, 2009, v. 92, p. S2, doi. 10.1111/j.1551-2916.2008.02722.x
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- Publication type:
- Article
Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis.
- Published in:
- BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1360-4
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- Publication type:
- Article
Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis
- Published in:
- BMC Cancer, 2015, v. 15, n. 1, p. 381, doi. 10.1186/s12885-015-1360-4
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- Publication type:
- Article
Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis.
- Published in:
- 2015
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- Publication type:
- journal article
Drug Release from Three-Dimensional Cubic Mesoporous Silica Nanoparticles Controlled by Nanoimpellers.
- Published in:
- Zeitschrift für Anorganische und Allgemeine Chemie, 2014, v. 640, n. 3/4, p. 588, doi. 10.1002/zaac.201300503
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- Publication type:
- Article
Reducing particle size of biodegradable nanomaterial for efficient curcumin loading.
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- Journal of Materials Science, 2021, v. 56, n. 5, p. 3713, doi. 10.1007/s10853-020-05504-7
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- Publication type:
- Article
Iodine containing porous organosilica nanoparticles trigger tumor spheroids destruction upon monochromatic X-ray irradiation: DNA breaks and K-edge energy X-ray.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-93429-9
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- Publication type:
- Article
Involvement of Lysosomal Exocytosis in the Excretion of Mesoporous Silica Nanoparticles and Enhancement of the Drug Delivery Effect by Exocytosis Inhibition.
- Published in:
- Small, 2013, v. 9, n. 5, p. 697, doi. 10.1002/smll.201201811
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- Publication type:
- Article
Synthesis of Biomolecule-Modified Mesoporous Silica Nanoparticles for Targeted Hydrophobic Drug Delivery to Cancer Cells.
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- Small, 2011, v. 7, n. 13, p. 1816, doi. 10.1002/smll.201002300
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- Publication type:
- Article
Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals.
- Published in:
- Small, 2010, v. 6, n. 16, p. 1794, doi. 10.1002/smll.201000538
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- Publication type:
- Article
Mesoporous Silica Nanoparticles Facilitate Delivery of siRNA to Shutdown Signaling Pathways in Mammalian Cells.
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- Small, 2010, v. 6, n. 11, p. 1185, doi. 10.1002/smll.200901966
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- Publication type:
- Article
Light-Activated Nanoimpeller-Controlled Drug Release in Cancer Cells.
- Published in:
- Small, 2008, v. 4, n. 4, p. 421, doi. 10.1002/smll.200700903
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- Publication type:
- Article
Mesoporous Silica Nanoparticles as a Delivery System for Hydrophobic Anticancer Drugs.
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- Small, 2007, v. 3, n. 8, p. 1341, doi. 10.1002/smll.200700005
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- Publication type:
- Article
A novel approach to tag and identify geranylgeranylated proteins.
- Published in:
- Electrophoresis, 2009, v. 30, n. 20, p. 3598, doi. 10.1002/elps.200900259
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- Publication type:
- Article
Two-Photon-Triggered Drug Delivery in Cancer Cells Using Nanoimpellers.
- Published in:
- Angewandte Chemie, 2013, v. 125, n. 51, p. 14058, doi. 10.1002/ange.201308647
- By:
- Publication type:
- Article
Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation.
- Published in:
- Glia, 2004, v. 47, n. 2, p. 180, doi. 10.1002/glia.20036
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- Publication type:
- Article
Spatial regulation of the exocyst complex by Rho1 GTPase.
- Published in:
- Nature Cell Biology, 2001, v. 3, n. 4, p. 353, doi. 10.1038/35070029
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- Publication type:
- Article
Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines.
- Published in:
- Oncogene, 2000, v. 19, n. 27, p. 3059, doi. 10.1038/sj.onc.1203625
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- Publication type:
- Article
Biodegradable Periodic Mesoporous Organosilica (BPMO) Loaded with Daunorubicin: A Promising Nanoparticle‐Based Anticancer Drug.
- Published in:
- ChemMedChem, 2020, v. 15, n. 7, p. 593, doi. 10.1002/cmdc.201900595
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- Publication type:
- Article
Significance of filamin A in mTORC2 function in glioblastoma.
- Published in:
- Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0396-z
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- Publication type:
- Article
Significance of filamin A in mTORC2 function in glioblastoma
- Published in:
- Molecular Cancer, 2015, v. 14, n. 1, p. 127, doi. 10.1186/s12943-015-0396-z
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- Publication type:
- Article
Biodegradable Oxamide-Phenylene-Based Mesoporous Organosilica Nanoparticles with Unprecedented Drug Payloads for Delivery in Cells.
- Published in:
- Chemistry - A European Journal, 2016, v. 22, n. 42, p. 14806, doi. 10.1002/chem.201601714
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- Publication type:
- Article
Frontispiece: Biodegradable Oxamide-Phenylene-Based Mesoporous Organosilica Nanoparticles with Unprecedented Drug Payloads for Delivery in Cells.
- Published in:
- Chemistry - A European Journal, 2016, v. 22, n. 42, p. n/a, doi. 10.1002/chem.201684261
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- Publication type:
- Article
Periodic Mesoporous Organosilica Nanoparticles with Controlled Morphologies and High Drug/Dye Loadings for Multicargo Delivery in Cancer Cells.
- Published in:
- Chemistry - A European Journal, 2016, v. 22, n. 28, p. 9607, doi. 10.1002/chem.201600587
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- Publication type:
- Article
Hybrid Mesoporous Silica Nanoparticles with pH-Operated and Complementary H-Bonding Caps as an Autonomous Drug-Delivery System.
- Published in:
- Chemistry - A European Journal, 2014, v. 20, n. 30, p. 9372, doi. 10.1002/chem.201402864
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- Publication type:
- Article
Fiber-Optic Based Laser Wakefield Accelerated Electron Beams and Potential Applications in Radiotherapy Cancer Treatments.
- Published in:
- Photonics, 2022, v. 9, n. 6, p. 403, doi. 10.3390/photonics9060403
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- Publication type:
- Article
Construction of Boronophenylalanine-Loaded Biodegradable Periodic Mesoporous Organosilica Nanoparticles for BNCT Cancer Therapy.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2251, doi. 10.3390/ijms22052251
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- Publication type:
- Article