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- Title
ICPS: an integrative cancer profiler system.
- Authors
Xin-yu Zhang; Lin Shi; Yan Liu; Feng Tian; Hai-tao Zhao; Xiao-ping Miao; Ming-lie Huang; Xiao-yan Zhu
- Abstract
Founded upon the database of 570 public signatures, ICPS is a web-based application to obtain biomarker profiles among 11 common cancers by integrating genomic alterations with transcription signatures on the basis of a previously developed integrative pipeline. ICPS supports both public data and user's in-house data, and performs meta-analysis at a cancer subtype level by combining heterogeneous datasets. Finally, ICPS returns the robust gene signature containing potential cancer biomarkers that may be useful to carcinogenesis study and clinical cancer diagnosis.Availability: http://server.bioicps.orgContact: zhxy@mail.tsinghua.edu.cn; zxy-dcs@mail.tsinghua.edu.cn
- Subjects
DATABASES; WORLD Wide Web; BIOMARKERS; GENOMICS; META-analysis; GENES
- Publication
Bioinformatics, 2010, Vol 26, Issue 20, p2649
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btq487