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- Title
An updated investigation on the antenatal development of the thyroid gland in white New Zealand rabbit with morphometric analysis.
- Authors
Moselhy, Attia A. A.; Nosseur, Hamed M.; El-Sayed, Sahar M.; Konsowa, Mervat M. H.
- Abstract
The prenatal development of the thyroid gland was studied on 30 rabbit embryos and fetuses of both sexes. Their ages ranged between 9 days old till the day of birth. The thyroid anlage appeared as an endodermal thickening in the floor of the primitive pharynx on the 9th day of gestation. On 11 days old embryos, the thyroid bud was connected to the pharyngeal endoderm by the thyroglossal duct which began to disintegrate on the 12th day of gestation. The bilobation of primitive thyroid gland was exhibited with the beginning of isthmus organization on the 16th days of gestation. The first evidence of follicular organization appeared at the 20th days of gestation with many small follicles disseminated within the gland. The first morphological sign of functional differentiation of the thyroid gland appeared on the 22nd days of gestation as PAS positive thick rim of pre colloid material in apical parts of the follicular cells in some follicles. Very few parafollicular cells began to scatter among follicular cells at the 22nd days old fetuses. The definitive thyroid follicles storing vacuolated typical colloid organized at the 28th days of gestation and stained somewhat strongly with Eosin and PAS.
- Subjects
THYROID gland; FETAL development; RABBITS; FETUS; ENDODERM; PREGNANCY
- Publication
Journal of Advanced Veterinary Research, 2024, Vol 14, Issue 3, p413
- ISSN
2090-6269
- Publication type
Article