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- Title
Circulating Tumor Cells: Magnetic "Squashing" of Circulating Tumor Cells on Plasmonic Substrates for Ultrasensitive NIR Fluorescence Detection (Small Methods 2/2019).
- Authors
Zhang, Ru; Le, Biao; Xu, Wei; Guo, Kai; Sun, Xuming; Su, Haiyang; Huang, Lin; Huang, Jingyi; Shen, Ting; Liao, Tao; Liang, Yongye; Zhang, John X. J.; Dai, Hongjie; Qian, Kun
- Abstract
In article number 1800474, John X. J. Zhang, Hongjie Dai, Kun Qian, and co‐workers, demonstrate that magnetic 'squashing' of circulating tumor cells (CTCs) on plasmonic substrates is achieved for ultrasensitive near‐infrared (NIR) fluorescence detection. Owing to the squashing of cells by magnetic forces and the resulting close proximity of NIR labels on cells to the plasmonic surface, an ultrahigh NIR fluorescence enhancement of ≈50–120 fold is observed, drastically enhancing the ability of CTC detection, imaging, and analysis.
- Subjects
BIOLOGICAL tags; MAGNETISM
- Publication
Small Methods, 2019, Vol 3, Issue 2, pN.PAG
- ISSN
2366-9608
- Publication type
Article
- DOI
10.1002/smtd.201970004