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- Title
Serratia infections in a general hospital: characteristics and outcomes.
- Authors
Samonis, G.; Vouloumanou, E.; Christofaki, M.; Dimopoulou, D.; Maraki, S.; Triantafyllou, E.; Kofteridis, D.; Falagas, M.
- Abstract
We aimed to present our experience regarding infections caused by Serratia spp. in a region with relatively high antimicrobial resistance rates. We retrospectively reviewed the databases of the microbiological laboratory of the University Hospital of Heraklion, Crete (2/2004-12/2009). A total of 77 patients [67.5% men, mean age ± standard deviation (SD) = 56.9 ± 24.5 years) were identified; 37.7% were outpatients. Sixty-five (84.4%) of the 77 included patients had a Serratia marcescens isolate; the remaining 12 patients had a non-marcescens Serratia spp. The most frequently observed infections were respiratory tract infection (32.5%) and keratitis/endophthalmitis (20.8%). Seventy-three (94.9%) patients were cured. Four deaths were observed; three of them were considered as attributed to the Serratia infection. No difference was found regarding the characteristics and outcomes between patients with Serratia marcescens and non-marcescens infections. In addition, antipseudomonal penicillins and their combinations with beta-lactamase inhibitors, as well as carbapenemes, and fluoroquinolones exhibited high antimicrobial activity against both the tested Serratia marcescens and non-marcescens isolates. Our study adds useful information regarding the characteristics and outcomes of patients with Serratia infection, as well as the susceptibilities of the respective Serratia marcescens and non-marcescens isolates, in a region with relatively high levels of antimicrobial resistance.
- Subjects
ERAKLEION (Greece); GREECE; SERRATIA diseases; ANTI-infective agents; UNIVERSITY hospitals
- Publication
European Journal of Clinical Microbiology & Infectious Diseases, 2011, Vol 30, Issue 5, p653
- ISSN
0934-9723
- Publication type
Article
- DOI
10.1007/s10096-010-1135-4