We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Obesity pandemics and the modification of digestive bacterial flora.
- Authors
Raoult, D.
- Abstract
Environmental factors, such as social networks, have an influence on obesity pandemics. The gut microbial flora (microbiota) plays a role in converting nutrients into calories. Variations in microbiota composition are found in obese humans and mice. The microbiota from an obese mouse confers an obese phenotype when transferred to an axenic mouse. There is a large body of experimental evidence and empirical data in the food industry showing that both antibiotics and probiotics, which modify the gut microbiota, can act as growth promoters, increasing the size and weight of animals. The current obesity pandemic may be caused, in part, by antibiotic treatments or colonization by probiotic bacteria. Using metagenomics and microarray analysis, studies of microbiota modifications after antibiotic and probiotic intake may identify the modifications associated with increased size and weight. Epidemiological studies recording these factors in an obese population may be able to link obesity with the absorption of microbiota modifiers.
- Subjects
OBESITY; NUTRITION disorders; METABOLIC disorders; OBESE-hyperglycemic syndrome; ADOLESCENT obesity; COMMUNICABLE diseases; PANDEMICS; EPIDEMIOLOGY; GENOTYPE-environment interaction; FOOD industry
- Publication
European Journal of Clinical Microbiology & Infectious Diseases, 2008, Vol 27, Issue 8, p631
- ISSN
0934-9723
- Publication type
Article
- DOI
10.1007/s10096-008-0490-x