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- Title
Portal vein diameter and spleen size as non-invasive predictors of esophageal varices in patients with viral cirrhosis.
- Authors
Panjwani, Rakesh; Sunder, Wish Lal; Kumar, Pawan; Hussain, Waqas; Kumar, Vijay; Kumar, Sundeep
- Abstract
Objective: To determine the frequency of esophageal varices in patients with cirrhosis and to evaluate the diagnostic value of mean spleen size and portal vein diameter for non-invasive detection of esophageal varices. Material and Methhods: Th is cross-sectional study was conducted at Medical Unit-I, Dr. Ruth K. M. Pfau Civil Hospital, Karachi from July 2016 to January 2017. A total of 200-patients with established cirrhosis were included. Th e severity of cirrohosis was classifi ed according to Child-Pugh classifi cation. Ultrasound was done to assess portal vein diameter and splenic measurements. Defi nitive diagnosis of esophageal varices was done on endoscopy. Data were entered and analyzed in SPSS version 21. Descriptive statistics and Chi-square test were applied. P-value ≤0.05 was taken as signifi cant. Results: Th ere were 132 (66%) males and 68 (34%) females. Out of 200-patients,155 (77.5%) were found to have esophageal varices on endoscopy. Overall, mean spleen size was 14.93 ± 2.99 cm and mean portal vein diameter, 1.23 ± 0.25 cm. Signifi cant association of esophageal varices was observed with age (p<0.001), duration of cirrhosis (p=0.010), Child-Pugh class (p=0.039) and etiology of liver cirrhosis (p<0.001) while no signifi cant association was observed with gender (p=0.411), BMI (p=0.300), residence (p=0.252), socio-economic status (p=0.262) and smoking (p=0.359). Statistically signifi cant diff erences were found in mean spleen size (p<0.001) and portal vein diameter(p<0.001) among patients with or without esophageal varices. Conclusion: In conclusion, spleen size and portal vein diameter may be used as reliable non-invasive predictors for the presence of esophageal varices among cirrhotic patients in resource-constrained sett ing.
- Subjects
KARACHI (Pakistan); ESOPHAGEAL varices; PORTAL vein; SPLEEN; CIRRHOSIS of the liver; ETIOLOGY of diseases
- Publication
Pakistan Journal of Surgery, 2020, Vol 36, Issue 1, p20
- ISSN
0258-8552
- Publication type
Article