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Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma.
Published in:
EMBO Molecular Medicine, 2022, v. 14, n. 3, p. 1, doi. 10.15252/emmm.202115295
By:
- Diazzi, Serena;
- Baeri, Alberto;
- Fassy, Julien;
- Lecacheur, Margaux;
- Marin‐Bejar, Oskar;
- Girard, Christophe A;
- Lefevre, Lauren;
- Lacoux, Caroline;
- Irondelle, Marie;
- Mounier, Carine;
- Truchi, Marin;
- Couralet, Marie;
- Ohanna, Mickael;
- Carminati, Alexandrine;
- Berestjuk, Ilona;
- Larbret, Frederic;
- Gilot, David;
- Vassaux, Georges;
- Marine, Jean‐Christophe;
- Deckert, Marcel
Publication type:
Article
Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix‐mediated tumor cell adaptation and tolerance to BRAF‐targeted therapy in melanoma.
Published in:
EMBO Molecular Medicine, 2022, v. 14, n. 2, p. 1, doi. 10.15252/emmm.201911814
By:
- Berestjuk, Ilona;
- Lecacheur, Margaux;
- Carminati, Alexandrine;
- Diazzi, Serena;
- Rovera, Christopher;
- Prod'homme, Virginie;
- Ohanna, Mickael;
- Popovic, Ana;
- Mallavialle, Aude;
- Larbret, Frédéric;
- Pisano, Sabrina;
- Audebert, Stéphane;
- Passeron, Thierry;
- Gaggioli, Cédric;
- Girard, Christophe A;
- Deckert, Marcel;
- Tartare‐Deckert, Sophie
Publication type:
Article
Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism.
Published in:
EMBO Molecular Medicine, 2009, v. 1, n. 3, p. 166, doi. 10.1002/emmm.200900018
By:
- Shimomura, Kenju;
- Flanagan, Sarah E.;
- Zadek, Brittany;
- Lethby, Mark;
- Zubcevic, Lejla;
- Girard, Christophe A. J.;
- Petz, Oliver;
- Mannikko, Roope;
- Kapoor, Ritika R.;
- Hussain, Khalid;
- Skae, Mars;
- Clayton, Peter;
- Hattersley, Andrew;
- Ellard, Sian;
- Ashcroft, Frances M.
Publication type:
Article
Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2–SUR1 interactions.
Published in:
EMBO Journal, 2005, v. 24, n. 13, p. 2318, doi. 10.1038/sj.emboj.7600715
By:
- Tammaro, Paolo;
- Girard, Christophe;
- Molnes, Janne;
- Njølstad, Pål R;
- Ashcroft, Frances M
Publication type:
Article
p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1.
Published in:
EMBO Journal, 2002, v. 21, n. 17, p. 4439, doi. 10.1093/emboj/cdf469
By:
- Girard, Christophe;
- Tinel, Norbert;
- Terrenoire, Cécile;
- Romey, Georges;
- Lazdunski, Michel;
- Borsotto, Marc
Publication type:
Article
Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.
Published in:
2009
By:
- Girard, Christophe A.;
- Wunderlich, F. Thomas;
- Shimomura, Kenju;
- Collins, Stephan;
- Kaizik, Stephan;
- Proks, Peter;
- Abdulkader, Fernando;
- Clark, Anne;
- Ball, Vicky;
- Zubcevic, Lejla;
- Bentley, Liz;
- Clark, Rebecca;
- Church, Chris;
- Hugill, Alison;
- Galvanovskis, Juris;
- Cox, Roger;
- Rorsman, Patrik;
- Brüning, Jens C.;
- Ashcroft, Frances M.;
- Brüning, Jens C
Publication type:
journal article
A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome.
Published in:
EMBO Reports, 2005, v. 6, n. 5, p. 470, doi. 10.1038/sj.embor.7400393
By:
- Proks, Peter;
- Girard, Christophe;
- Haider, Shozeb;
- Gloyn, Anna L.;
- Hattersley, Andrew T.;
- Sansom, Mark S. P.;
- Ashcroft, Frances M.
Publication type:
Article
Nouveaux rôles physiopathologiques pour le récepteur PLA2R1 dans le cancer et la glomérulonéphrite extramembraneuse.
Published in:
Médecine Sciences, 2014, v. 30, n. 5, p. 519, doi. 10.1051/medsci/20143005014
By:
- Girard, Christophe A.;
- Seitz-Polski, Barbara;
- Dolla, Guillaume;
- Augert, Arnaud;
- Vindrieux, David;
- Bernard, David;
- Lambeau, Gérard
Publication type:
Article
Overexpression of Fto leads to increased food intake and results in obesity.
Published in:
Nature Genetics, 2010, v. 42, n. 12, p. 1086, doi. 10.1038/ng.713
By:
- Church, Chris;
- Moir, Lee;
- McMurray, Fiona;
- Girard, Christophe;
- Banks, Gareth T.;
- Teboul, Lydia;
- Wells, Sara;
- Brüning, Jens C.;
- Nolan, Patrick M.;
- Ashcroft, Frances M.;
- Cox, Roger D.
Publication type:
Article
Atomic and electronic structure of trilayer graphene/SiC(0001): Evidence of Strong Dependence on Stacking Sequence and charge transfer.
Published in:
Scientific Reports, 2016, p. 33487, doi. 10.1038/srep33487
By:
- Pierucci, Debora;
- Brumme, Thomas;
- Girard, Jean-Christophe;
- Calandra, Matteo;
- Silly, Mathieu G.;
- Sirotti, Fausto;
- Barbier, Antoine;
- Mauri, Francesco;
- Ouerghi, Abdelkarim
Publication type:
Article
Inhibition of Patched Drug Efflux Increases Vemurafenib Effectiveness against Resistant BrafV600E Melanoma.
Published in:
Cancers, 2020, v. 12, n. 6, p. 1500, doi. 10.3390/cancers12061500
By:
- Signetti, Laurie;
- Elizarov, Nelli;
- Simsir, Méliné;
- Paquet, Agnès;
- Douguet, Dominique;
- Labbal, Fabien;
- Debayle, Delphine;
- Di Giorgio, Audrey;
- Biou, Valérie;
- Girard, Christophe;
- Duca, Maria;
- Bretillon, Lionel;
- Bertolotto, Corine;
- Verrier, Bernard;
- Azoulay, Stéphane;
- Mus-Veteau, Isabelle
Publication type:
Article
Functional analysis of six Kir6.2 ( KCNJ11) mutations causing neonatal diabetes.
Published in:
Pflügers Archiv: European Journal of Physiology, 2006, v. 453, n. 3, p. 323, doi. 10.1007/s00424-006-0112-3
By:
- Girard, Christophe;
- Shimomura, Kenju;
- Proks, Peter;
- Absalom, Nathan;
- Castano, Luis;
- de Nanclares, Guiomar;
- Ashcroft, Frances
Publication type:
Article
When Competitive Intelligence Meets Geospatial Intelligence.
Published in:
International Journal of Business Intelligence Research, 2015, v. 6, n. 2, p. 33, doi. 10.4018/IJBIR.2015070103
By:
- Othenin-Girard, Christophe;
- Guillemette, Manon G.;
- Foley, Eric;
- Caron, Claude
Publication type:
Article
Superconducting parity effect across the Anderson limit.
Published in:
Nature Communications, 2017, v. 8, n. 2, p. 14549, doi. 10.1038/ncomms14549
By:
- Vlaic, Sergio;
- Pons, Stéphane;
- Zhang, Tianzhen;
- Assouline, Alexandre;
- Zimmers, Alexandre;
- David, Christophe;
- Rodary, Guillemin;
- Girard, Jean-Christophe;
- Roditchev, Dimitri;
- Aubin, Hervé
Publication type:
Article
Mosaic paternal uniparental isodisomy and an ABCC8 gene mutation in a patient with permanent neonatal diabetes and hemihypertrophy.
Published in:
2008
By:
- Shield JP;
- Flanagan SE;
- Mackay DJ;
- Harries LW;
- Proks P;
- Girard C;
- Ashcroft FM;
- Temple IK;
- Ellard S;
- Shield, Julian P H;
- Flanagan, Sarah E;
- Mackay, Deborah J;
- Harries, Lorna W;
- Proks, Peter;
- Girard, Christophe;
- Ashcroft, Frances M;
- Temple, I Karen;
- Ellard, Sian
Publication type:
journal article
Mosaic Paternal Uniparentat Isodisomy and an ABCC8 Gene Mutation in a Patient With Permanent Neonatal Diabetes and Hemihypertrophy.
Published in:
Diabetes, 2008, v. 57, n. 1, p. 255, doi. 10.2337/db07-0999
By:
- Shield, Julian P. H.;
- Flanagan, Sarah E.;
- Mackay, Deborah J.;
- Harries, Lorna W.;
- Proks, Peter;
- Girard, Christophe;
- Ashcroft, Frances M.;
- Temple, I. Karen;
- Ellard, Sian
Publication type:
Article
ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic beta-cells.
Published in:
2006
By:
- Tarasov AI;
- Girard CA;
- Ashcroft FM;
- Tarasov, Andrei I;
- Girard, Christophe A J;
- Ashcroft, Frances M
Publication type:
journal article
ATP Sensitivity of the ATP-Sensitive K+ Channel in Intact and Permeabilized Pancreatic β-Cells.
Published in:
Diabetes, 2006, v. 55, n. 9, p. 2446, doi. 10.2337/db06-0360
By:
- Tarasov, Andrei I.;
- Girard, Christophe A. J.;
- Ashcroft, Frances M.
Publication type:
Article
Functional Effects of Mutations at F35 in the NH2-terminus of Kir6.2 (KCNJ11), Causing Neonatal Diabetes, and Response to Sulfonylurea Therapy.
Published in:
Diabetes, 2006, v. 55, n. 6, p. 1731, doi. 10.2337/db05-1420
By:
- Proks, Peter;
- Girard, Christophe;
- Bævre, Halvor;
- Njølstad, Pål R.;
- Ashcroft, Frances M.
Publication type:
Article
Mutations at the Same Residue (R50) of Kir6.2 (KCNJ11) That Cause Neonatal Diabetes Produce Different Functional Effects.
Published in:
Diabetes, 2006, v. 55, n. 6, p. 1705, doi. 10.2337/db05-1640
By:
- Shimomura, Kenju;
- Girard, Christophe A. J.;
- Proks, Peter;
- Nazim, Joanna;
- Lippiat, Jonathan D.;
- Cerutti, Franco;
- Lorini, Renata;
- Ellard, Sian;
- Hattersely, Andrew T.;
- Barbetti, Fabrizio;
- Ashcroft, Frances M.
Publication type:
Article
A COMBINED FDTD/TLM TIME DOMAIN METHOD TO SOLVE EFFICIENTLY ELECTROMAGNETIC PROBLEMS.
Published in:
Progress in Electromagnetics Research B, 2013, v. 56, p. 409, doi. 10.2528/pierb13092402
By:
- Muot, Nathanael;
- Girard, Christophe;
- Ferrieres, Xavier;
- Bachelier, Elodie
Publication type:
Article
Mechanism of action of a sulphonylurea receptor SUR1 mutation (F132L) that causes DEND syndrome.
Published in:
Human Molecular Genetics, 2007, v. 16, n. 16, p. 2011, doi. 10.1093/hmg/ddm149
By:
- Proks, Peter;
- Shimomura, Kenju;
- Craig, Tim J.;
- Girard, Christophe A.J.;
- Ashcroft, Frances M.
Publication type:
Article
A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes.
Published in:
Human Molecular Genetics, 2006, v. 15, n. 11, p. 1793, doi. 10.1093/hmg/ddl101
By:
- Proks, Peter;
- Arnold, Amanda L.;
- Bruining, Jan;
- Girard, Christophe;
- Flanagan, Sarah E.;
- Larkin, Brian;
- Colclough, Kevin;
- Hattersley, Andrew T.;
- Ashcroft, Frances M.;
- Ellard, Sian
Publication type:
Article
Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP.
Published in:
Human Molecular Genetics, 2005, v. 14, n. 18, p. 2717, doi. 10.1093/hmg/ddi305
By:
- Proks, Peter;
- Girard, Christophe;
- Ashcroft, Frances M.
Publication type:
Article
Relapsing diabetes can result from moderately activating mutations in KCNJ11.
Published in:
Human Molecular Genetics, 2005, v. 14, n. 7, p. 925, doi. 10.1093/hmg/ddi086
By:
- Gloyn, Anna L.;
- Reimann, Frank;
- Girard, Christophe;
- Edghill, Emma L.;
- Proks, Peter;
- Pearson, Ewan R.;
- Temple, I. Karen;
- Mackay, Deborah J.G.;
- Shield, Julian P.H.;
- Freedenberg, Debra;
- Noyes, Kathryn;
- Ellard, Sian;
- Ashcroft, Frances M.;
- Gribble, Fiona M.;
- Hattersley, Andrew T.
Publication type:
Article
Aerobic Alcohol Oxidations Mediated by Nitric Acid.
Published in:
Angewandte Chemie International Edition, 2011, v. 50, n. 51, p. 12355, doi. 10.1002/anie.201105620
By:
- Aellig, Christof;
- Girard, Christophe;
- Hermans, Ive
Publication type:
Article

Found: 26

Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma.

Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix‐mediated tumor cell adaptation and tolerance to BRAF‐targeted therapy in melanoma.

Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism.

Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2–SUR1 interactions.

p11, an annexin II subunit, an auxiliary protein associated with the background K<sup>+</sup> channel, TASK-1.

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.

A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome.

Nouveaux rôles physiopathologiques pour le récepteur PLA2R1 dans le cancer et la glomérulonéphrite extramembraneuse.

Overexpression of Fto leads to increased food intake and results in obesity.

Atomic and electronic structure of trilayer graphene/SiC(0001): Evidence of Strong Dependence on Stacking Sequence and charge transfer.

Inhibition of Patched Drug Efflux Increases Vemurafenib Effectiveness against Resistant BrafV600E Melanoma.

Functional analysis of six Kir6.2 ( KCNJ11) mutations causing neonatal diabetes.

When Competitive Intelligence Meets Geospatial Intelligence.

Superconducting parity effect across the Anderson limit.

Mosaic paternal uniparental isodisomy and an ABCC8 gene mutation in a patient with permanent neonatal diabetes and hemihypertrophy.

Mosaic Paternal Uniparentat Isodisomy and an ABCC8 Gene Mutation in a Patient With Permanent Neonatal Diabetes and Hemihypertrophy.

ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic beta-cells.

ATP Sensitivity of the ATP-Sensitive K<sup>+</sup> Channel in Intact and Permeabilized Pancreatic β-Cells.

Functional Effects of Mutations at F35 in the NH<sub>2</sub>-terminus of Kir6.2 (KCNJ11), Causing Neonatal Diabetes, and Response to Sulfonylurea Therapy.

Mutations at the Same Residue (R50) of Kir6.2 (KCNJ11) That Cause Neonatal Diabetes Produce Different Functional Effects.

A COMBINED FDTD/TLM TIME DOMAIN METHOD TO SOLVE EFFICIENTLY ELECTROMAGNETIC PROBLEMS.

Mechanism of action of a sulphonylurea receptor SUR1 mutation (F132L) that causes DEND syndrome.

A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes.

Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP.

Relapsing diabetes can result from moderately activating mutations in KCNJ11.

Aerobic Alcohol Oxidations Mediated by Nitric Acid.