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- Title
New Mode for the Determination of Ketotifen Fumarate Using Low Pressure Mercury Lamp via Continuous Flow Injection Analysis.
- Authors
Al-banaa, Marwah A. Kadhim
- Abstract
The method was based on the quenched of continuous fluorescence of fluorescence dye (N-(4-Aryl diazenyl-p-phenol-1,8-naphthal imide) that were used for determination of ketotifen fumarate. A comprehensive detailed study was carried out by ISNAG-fluorimeter CFIA that capable of measuring fluorescence emitted from fluorescent molecules that be excited by low mercury lamps. The linearity range, r,r2,R2% and limit of detection were : 0.01-10mmol.L-1 , 0.9837 ,0.9676 , 96.76 and 0.425 μg/125μL.Pure and pharmaceutical formulation of mentioned drug was analyzed successfully in this work . A comparison was made between the official quoted value and the practically found values for the three kinds of drug by individual t-test. Individual t-test reveals that there was no significant difference between both means (quoted value with calculated t-value) from developed method.
- Subjects
FLOW injection analysis; KETOTIFEN; MERCURY; LAMPS; PRESSURE
- Publication
Systematic Reviews in Pharmacy, 2020, Vol 11, Issue 2, p395
- ISSN
0975-8453
- Publication type
Article
- DOI
10.5530/srp.2020.2.58