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- Title
ASSESSMENT OF GENOTOXICITY AND DEPURATION OF ANTHRACENE IN THE JUVENILE COASTAL FISH Trachinotus carolinus USING THE COMET ASSAY.
- Authors
Matsu Hasue, Fabio; de Arruda Campos Rocha Passos, Maria José; da Cruz Alves dos Santos, Thaís; da Silva Rocha, Arthur José; Vignardi, Caroline Patrício; Sartorio, Priscila Verônica; Gomes, Vicente; Phan Van Ngan
- Abstract
In the environment, anthracene is characterized as being persistent, bioaccumulative and toxic to aquatic organisms. Biotransformation of xenobiotic substances, such as anthracene, produces reactive oxygen species that may induce DNA strand breaks. The aim of the present study was to evaluate the DNA damage in juvenile T. carolinus exposed to different concentrations (8, 16 and 32 μg.L-1) of anthracene for 24 h in the dark then subsequently allowed to depurate in clean water for different periods of time (48, 96 or 144 h) using the comet assay. Our results show that anthracene is genotoxic to T. carolinus and that DNA damage was dose- and depuration/time- dependent. Anthracene genotoxicity was observed in all experimental concentrations. Depuration seemed to be more efficient in fish exposed to the lowest anthracene concentration and maintained in clean water for 96 h.
- Subjects
FISHERIES; MARINE fishes; POLYCYCLIC aromatic hydrocarbons; ANTHRACENE; DNA damage; BIOCHEMICAL genetics; REACTIVE oxygen species
- Publication
Brazilian Journal of Oceanography, 2013, Vol 61, Issue 4, p215
- ISSN
1679-8759
- Publication type
Article
- DOI
10.1590/S1679-87592013000400002