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- Title
Clinical Features of and Risk Factors for Hydrocephalus in Childhood Bacterial Meningitis.
- Authors
Huo, Liang; Fan, Yuying; Jiang, Chunying; Gao, Jian; Yin, Meng; Wang, Hua; Yang, Fenghua; Cao, Qingjun
- Abstract
Objective: To explore the clinical characteristics of and analyze the risk factors for hydrocephalus in children with bacterial meningitis. Methods: Retrospective study of a sample of children with bacterial meningitis seen on the pediatric service of Shengjing Hospital of China Medical University between January 1, 2010, and December 31, 2016. Results: Overall, 9.36% (25/267) of patients presented with hydrocephalus. Among patients with hydrocephalus, the age at onset of bacterial meningitis was usually <6 months, 15 patients had confirmed bacterial etiology, and 1 patient died. The most significant results of multivariate analysis for hydrocephalus were a rural living situation, altered level of consciousness, previous treatment with antibiotics, initial cerebrospinal fluid protein >2 g/L, C-reactive protein >100 mg/L, and dexamethasone use. Conclusions: A severe clinical manifestation and significant laboratory index at admission are the most important predictors of hydrocephalus in children with bacterial meningitis.
- Subjects
HYDROCEPHALUS in children; BACTERIAL meningitis; BACTERIAL diseases; CEREBROSPINAL fluid; ETIOLOGY of diseases
- Publication
Journal of Child Neurology, 2019, Vol 34, Issue 1, p11
- ISSN
0883-0738
- Publication type
Article
- DOI
10.1177/0883073818799155