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- Title
Improved extremity tissue oxygenation with short-term exposure to textiles embedded with far infrared light emitting thermoactive particles in patients with diabetes mellitus.
- Authors
Athonvarangkul, Diana; Wang, Kaicheng; Deng, Yanhong; Inzucchi, Silvio E; Mayerson, Adam
- Abstract
Use of far infrared (FIR) energy may improve peripheral circulation. This study aimed to determine whether FIR delivered through textiles improves peripheral microcirculation as measured by transcutaneous oximetry (TcPO2) in individuals with diabetes mellitus (DM). Methods: A single-center, prospective, randomized, placebo-controlled, double-blinded, crossover study of 32 subjects with either type 1 or type 2 DM. An active FIR wrap followed by a placebo wrap (or vice versa) was applied to the arm, calf, ankle, and forefoot for 60 min each with continuous TcPO2 measurements. The treatment effect of the active versus placebo wrap was estimated using a linear mixed effect model adjusted for period, sequence, baseline value, and anatomic site. Results: The active FIR wrap increased mean TcPO2 at the arm (2.6 ± 0.8 mmHg, p =.002), calf (1.5 ± 0.7 mmHg, p =.03), and ankle (1.7 ± 0.8 mmHg, p =.04) and composite of all sites (1.4 ± 0.5 mmHg, p =.002) after 60 min. The estimated treatment effect was significant for the active FIR wrap at the calf (1.5 ± 0.7 mmHg, p =.045) and in composite of all sites (1.2 ± 0.5 mmHg, p =.013). Conclusion: Short-term exposure to FIR textiles improves peripheral tissue oxygenation in patients with diabetes.
- Subjects
TYPE 2 diabetes; DIABETES; PEOPLE with diabetes; OXYGEN in the blood; PERIPHERAL circulation
- Publication
Diabetes & Vascular Disease Research, 2023, Vol 20, Issue 2, p1
- ISSN
1479-1641
- Publication type
Article
- DOI
10.1177/14791641231170282