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Innovation: Rescuing drug discovery: in vivo systems pathology and systems pharmacology.
- Published in:
- Nature Reviews Drug Discovery, 2005, v. 4, n. 12, p. 961, doi. 10.1038/nrd1904
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- Article
Feasibility of electroextraction as versatile sample preconcentration for fast and sensitive analysis of urine metabolites, demonstrated on acylcarnitines.
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- Electrophoresis, 2012, v. 33, n. 19/20, p. 2987, doi. 10.1002/elps.201200276
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- Article
Online capillary liquid-liquid electroextraction of peptides as fast pre-concentration prior to LC-MS.
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- Electrophoresis, 2010, v. 31, n. 23/24, p. 3903, doi. 10.1002/elps.201000347
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- Article
Feasibility of electrodialysis as a fast and selective sample preparation method for the profiling of low-abundant peptides in biofluids.
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- Electrophoresis, 2009, v. 30, n. 13, p. 2284, doi. 10.1002/elps.200800500
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- Article
CE-ESI-MS of biological anions in plastic capillaries at high pH.
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- Electrophoresis, 2007, v. 28, n. 6, p. 944, doi. 10.1002/elps.200600461
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- Article
Capillary isoelectric focusing-mass spectrometry for shotgun approach in proteomics.
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- Electrophoresis, 2004, v. 25, n. 20, p. 3461, doi. 10.1002/elps.200406087
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- Article
Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma.
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- Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/543541
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- Article
Automated capillary electrochromatography tandem mass spectrometry using mixed mode reversed-phase ion-exchange chromatography columns.
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- Rapid Communications in Mass Spectrometry: RCM, 1999, v. 13, n. 3, p. 141, doi. 10.1002/(SICI)1097-0231(19990215)13:3<141::AID-RCM467>3.0.CO;2-O
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- Article
Developing computational model-based diagnostics to analyse clinical chemistry data.
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- Briefings in Bioinformatics, 2010, v. 11, n. 4, p. 403, doi. 10.1093/bib/bbp071
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- Article
Of Monkeys and Men: A Metabolomic Analysis of Static and Dynamic Urinary Metabolic Phenotypes in Two Species.
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- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106077
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- Article
Network Identification of Hormonal Regulation.
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- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096284
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- Article
Lipoprotein Metabolism Indicators Improve Cardiovascular Risk Prediction.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092840
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- Article
Ultraweak Photon Emission as a Non-Invasive Health Assessment: A Systematic Review.
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- PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087401
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- Article
Imaging of Ultra-Weak Photon Emission in a Rheumatoid Arthritis Mouse Model.
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- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084579
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- Article
Characterization of Rheumatoid Arthritis Subtypes Using Symptom Profiles, Clinical Chemistry and Metabolomics Measurements.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044331
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- Article
Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice.
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- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030332
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- Article
Sub-Typing of Rheumatic Diseases Based on a Systems Diagnosis Questionnaire.
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- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024846
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- Article
Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice.
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- PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019423
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- Publication type:
- Article
Metabolic Profiling of the Response to an Oral Glucose Tolerance Test Detects Subtle Metabolic Changes.
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- PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004525
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- Article
Hierarchical clustering analysis of blood plasma lipidomics profiles from mono- and dizygotic twin families.
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- European Journal of Human Genetics, 2013, v. 21, n. 1, p. 95, doi. 10.1038/ejhg.2012.110
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- Article
Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives.
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- Metabolomics, 2011, v. 7, n. 3, p. 307, doi. 10.1007/s11306-010-0254-3
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- Article
Statistical validation of megavariate effects in ASCA.
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- BMC Bioinformatics, 2007, v. 8, p. 322, doi. 10.1186/1471-2105-8-322
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- Article
Separation and identification of platinum adducts with DNA nucleotides by capillary zone electrophoresis and capillary zone electrophoresis coupled to mass spectrometry.
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- Electrophoresis, 2001, v. 22, n. 1, p. 97, doi. 10.1002/1522-2683(200101)22:1<97::AID-ELPS97>3.0.CO;2-Y
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- Article
Recent methodology in the phytochemical analysis of ginseng.
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- Phytochemical Analysis, 2008, v. 19, n. 1, p. 2, doi. 10.1002/pca.1049
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- Article
Crossing the Boundaries of Our Current Healthcare System by Integrating Ultra-Weak Photon Emissions with Metabolomics.
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- 2016
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- Publication type:
- Essay
Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study.
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- BMC Medical Genomics, 2010, v. 3, p. 5, doi. 10.1186/1755-8794-3-5
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- Article
Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology.
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- Phytotherapy Research, 2005, v. 19, n. 3, p. 173, doi. 10.1002/ptr.1624
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- Article
Proteome analysis of the medicinal plant Catharanthus roseus.
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- Planta: An International Journal of Plant Biology, 2005, v. 221, n. 5, p. 690, doi. 10.1007/s00425-004-1474-4
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- Article
ASCA: analysis of multivariate data obtained from an experimental design.
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- Journal of Chemometrics, 2005, v. 19, n. 9, p. 469, doi. 10.1002/cem.952
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- Article
Symbiosis of chemometrics and metabolomics: past, present, and future.
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- Journal of Chemometrics, 2005, v. 19, n. 5-7, p. 376, doi. 10.1002/cem.941
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- Article
Considerations for proteolytic labeling-optimization of <sup>18</sup>O incorporation and prohibition of back-exchange.
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- Rapid Communications in Mass Spectrometry: RCM, 2006, v. 20, n. 23, p. 3491, doi. 10.1002/rcm.2738
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- Article
On-target fraction collection for the off-line coupling of capillary isoelectric focusing with matrix-assisted laser desorption/ionization mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2002, v. 16, n. 3, p. 201, doi. 10.1002/rcm.566
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- Publication type:
- Article
In-line coupling of low-pressure short capillary electrochromatography columns to electrospray ionisation mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2001, v. 15, n. 11, p. 878, doi. 10.1002/rcm.291
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- Article
Chip-based capillary electrophoresis with an electrodeless nanospray interface.
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- Rapid Communications in Mass Spectrometry: RCM, 2000, v. 14, n. 18, p. 1682, doi. 10.1002/1097-0231(20000930)14:18<1682::AID-RCM78>3.0.CO;2-E
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- Article
Capillary electrochromatography/nanoelectrospray mass spectrometry for attomole characterization of peptides.
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- Rapid Communications in Mass Spectrometry: RCM, 2000, v. 14, n. 16, p. 1448, doi. 10.1002/1097-0231(20000830)14:16<1448::AID-RCM44>3.0.CO;2-9
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- Publication type:
- Article
A free-flow electrophoresis chip device for interfacing capillary isoelectric focusing on-line with electrospray mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2000, v. 14, n. 14, p. 1269, doi. 10.1002/1097-0231(20000730)14:14<1269::AID-RCM24>3.0.CO;2-F
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- Article
Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers.
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- British Journal of Clinical Pharmacology, 2007, v. 63, n. 5, p. 562, doi. 10.1111/j.1365-2125.2006.02816.x
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- Publication type:
- Article
Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis.
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- PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163087
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- Article
Looking back into the future: 30 years of metabolomics at TNO.
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- Mass Spectrometry Reviews, 2013, v. 32, n. 5, p. 399, doi. 10.1002/mas.21370
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- Article
All systems go.
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- Nature, 2011, v. 480, n. 7378, p. S87, doi. 10.1038/480S87a
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- Article
ANOVA-simultaneous component analysis (ASCA): a new tool for analyzing designed metabolomics data.
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- Bioinformatics, 2005, v. 21, n. 13, p. 3043, doi. 10.1093/bioinformatics/bti476
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- Article
Analysis of longitudinal metabolomics data.
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- Bioinformatics, 2004, v. 20, n. 15, p. 2438, doi. 10.1093/bioinformatics/bth268
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- Publication type:
- Article
Metabolomics profiling of the free and total oxidised lipids in urine by LC-MS/MS: application in patients with rheumatoid arthritis.
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- Analytical & Bioanalytical Chemistry, 2016, v. 408, n. 23, p. 6307, doi. 10.1007/s00216-016-9742-2
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- Article
Grip on health: A complex systems approach to transform health care.
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- Journal of Evaluation in Clinical Practice, 2018, v. 24, n. 1, p. 269, doi. 10.1111/jep.12679
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- Article
Corrigendum to: <B>Establishment of the enzymatic protein acetylation independent of acetyl CoA: recombinant glutathione S-transferase 3-3 is acetylated by a novel membrane-bound transacetylase using 7,8-diacetoxy-4-methyl coumarin as the acetyl donor</B> (FEBS 26626): [FEBS Letters 530 (2002) 139–142]
- Published in:
- 2002
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- Publication type:
- Correction Notice
Establishment of the enzymatic protein acetylation independent of acetyl CoA: recombinant glutathione S-transferase 3-3 is acetylated by a novel membrane-bound transacetylase using 7,8-diacetoxy-4-methyl coumarin as the acetyl donor
- Published in:
- FEBS Letters, 2002, v. 530, n. 1-3, p. 139, doi. 10.1016/S0014-5793(02)03445-2
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- Publication type:
- Article