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- Title
The management of CKD: A look into the future.
- Authors
Khwaja, A.; El Kossi, M.; Floege, J.; El Nahas, M.
- Abstract
The increasing global prevalence of chronic kidney disease (CKD) and end-stage renal disease with the associated spiraling cost has profound public health and economic implications. This has made slowing the progression of CKD, a major health-care priority. CKD is invariably characterized by progressive kidney fibrosis and at present, treatment aiming to slow the progression of CKD is limited to aggressive blood pressure control, with few therapies targeting the fibrotic process itself. In this review, we explore the potential of experimental therapeutic strategies, based on preventing or reversing the pathophysiologic steps of kidney remodeling that lead to fibrosis.Kidney International (2007) 72, 1316–1323; doi:10.1038/sj.ki.5002489; published online 15 August 2007
- Subjects
CHRONIC kidney failure; KIDNEY diseases; CHRONIC diseases; VITAL signs; ACUTE kidney failure
- Publication
Kidney International, 2007, Vol 72, Issue 11, p1316
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/sj.ki.5002489