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- Title
The impact of HIV on chronic kidney disease outcomes.
- Authors
Choi, A. I.; Rodriguez, R. A.; Bacchetti, P.; Bertenthal, D.; Volberding, P. A.; O'Hare, A. M.
- Abstract
Chronic kidney disease (CKD) is a known complication of the human immunodeficiency virus (HIV) but outcomes among HIV-infected patients with kidney disease are unknown. We studied a national sample of 202 927 patients with CKD (stage 3 or higher) for death, end-stage renal disease (ESRD) and the mean annual rate of decline in estimated glomerular filtration rate (eGFR) over a median period of 3.8 years. Within this sample, 0.3% of the patients were diagnosed with HIV, 43.5% were diabetic, whereas the remainder had neither disease. In this national CKD cohort, HIV-infected black patients were at higher risk of death, a similar risk for ESRD and loss of eGFR than black patients with diabetes. HIV-infected white patients experienced higher rates of death but a lower risk of ESRD than their counterparts with diabetes. Our results highlight a need to study mortality and mechanisms of ESRD in the HIV infected population.Kidney International (2007) 72, 1380–1387; doi:10.1038/sj.ki.5002541; published online 5 September 2007
- Subjects
HIV-positive persons; HIV infections; CHRONIC kidney failure; HIV; KIDNEY diseases; ENDOCRINE diseases
- Publication
Kidney International, 2007, Vol 72, Issue 11, p1380
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/sj.ki.5002541