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- Title
Liver Failure after Hydroxycut™ Use in a Patient with Undiagnosed Hereditary Coproporphyria.
- Authors
Haimowitz, Stephanie; Hsieh, Jennifer; Shcherba, Marina; Averbukh, Yelena
- Abstract
We report the case of a young male presenting with cholestatic liver failure. After an extensive workup, the etiology of the liver failure was determined to be due to hereditary coprophorphyria (HCP). The inciting event was the use of Hydroxycut™, an over-the-counter supplement to promote weight loss that has been reported to cause oxidative liver injury in vulnerable populations. Although HCP is a rare cause of cholestatic liver failure, it is treatable if diagnosed correctly and in a timely manner. In this clinical vignette, we discuss a case that highlights the genetic susceptibility to disease that can be unmasked by environmental exposures. We also review the relevant literature on Hydroxycut™ and how it can affect hepatic function.
- Subjects
LIVER failure; GENETIC disorders; HEPATIC artery physiology; LIVER injuries; VIGNETTES; THERAPEUTICS
- Publication
JGIM: Journal of General Internal Medicine, 2015, Vol 30, Issue 6, p856
- ISSN
0884-8734
- Publication type
Article
- DOI
10.1007/s11606-014-3153-x