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- Title
Plants defective in calcium oxalate crystal formation have more bioavailable calcium.
- Authors
Hirschi, Kendal D.; Morris, Jay; Nakata, Paul A.; McConn, Michelle; Brock, Amanda
- Abstract
Bioavailable calcium affects bone formation and calcification. Here we investigate how a single gene mutation altering calcium partitioning in the forage crop Medicago truncatula affects calcium bioavailability. Previously, the cod5 Medicago mutant was identified which contains wild-type amounts of calcium, but none partitioned into oxalate crystals. We fed M. truncatula and cod5 extrinsically and intrinsically labeled 45Ca-containing diets to mice, and absorption of the tracer was determined in the legs one day after consumption. In the intrinsically labeled diets, calcium absorption was 22.87% higher in mice fed cod5. Our study presents genetic evidence demonstrating the nutritional impact of removing oxalate crystals from foods.
- Subjects
CALCIUM oxalate; CALCIUM; FORAGE plants; BONES; CALCIFICATION; GENETIC mutation; BIOAVAILABILITY
- Publication
FASEB Journal, 2007, Vol 21, Issue 5, pA356
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fasebj.21.5.a356