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- Title
Objectively measured physical activity is independently associated with insulin resistance in children after adjusting for epidemiological estimates of body composition.
- Authors
Arngrímsson, Sigurbjörn Árni; Sveinsson, Torarinn; Gunnarsdóttir, Ingibjörg; Pálsson, Gestur I.; Thorsdottir, Inga; Jóhannsson, Erlingur
- Abstract
The relationship between physical activity (PA), body composition, and insulin resistance in children and adolescents was determined in a population based sample (n = 152) of 9 (34 boys, 42 girls) and 15 (43 boys, 33 girls) year-olds from 18 randomly selected schools in Iceland. Body composition was assessed via body mass index (BMI), waist circumference adjusted for height (Waistadj), and sum of 4 skinfolds (SKF). PA (counts/day) was measured with accelerometers and fasting insulin (index of insulin resistance) was assessed via ECLIA. Sexual maturity was determined by self-reported Tanner staging. Fasting insulin was related to all body composition variables (r = 0.41-0.52, p < 0.01) and PA (r = -0.19, p = 0.02) after adjusting for age, Tanner stage, and gender with SKF being the best predictor of insulin resistance. Statistical control for PA did not affect the relations between body composition and fasting insulin (r = 0.41-0.50, p < 0.01). Similarly, PA remained significantly related to fasting insulin after adjustiSTYLES BM1 (r = -0.18, p = 0.03) and Waistadj (r = -0.16, p = 0.05) but not SKF (r = -0.08, p = 0.33). PA is an independent predictor of insulin resistance in children and adolescents after adjusting for commonly used epidemiological indices of body composition; however, better measures of obesity may abolish this relationship.
- Subjects
ICELAND; EXERCISE; INSULIN resistance; HUMAN body composition; CHILDREN; TEENAGERS; EPIDEMIOLOGY
- Publication
FASEB Journal, 2007, Vol 21, Issue 5, pA167
- ISSN
0892-6638
- Publication type
Article